iPTMnet Report Q8WTV0 SCARB1

Protein Information

Cytoscape View

UniProt AC / UniProt ID	Q8WTV0 / SCRB1_HUMAN
Protein Name	Scavenger receptor class B member 1
Gene Name	Name: SCARB1 Synonyms:CD36L1,CLA1;
Organism	Homo sapiens (Human)

PRO ID	PR:Q8WTV0 DAG View
PRO Name	scavenger receptor class B member 1 (human)
Definition	A scavenger receptor class B member 1 that is encoded in the genome of human.
Short Label	hSCARB1
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

Q8WTV0 (SCARB1) as Substrate

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	K42	Ubiquitination		score1	PhosphoSitePlus
	N54	N-Glycosylation		score1	GlyGen	24190977
	Y92	Phosphorylation		score1	PhosphoSitePlus
	N102	N-Glycosylation		score2	GlyGen UniProt	19159218, 24190977
	N106	N-Glycosylation		score1	GlyGen	24190977
	N107	N-Glycosylation		score1	GlyGen	24190977
	N108	N-Glycosylation		score1	GlyGen	24190977
	T175	Phosphorylation		score1	PhosphoSitePlus
	N227	N-Glycosylation		score1	GlyGen	29741879
	C251	Methylation		score1	IEDB	31844290
	C280	Methylation		score1	IEDB	31844290
	K284	Ubiquitination		score1	PhosphoSitePlus
	K288	Ubiquitination		score1	PhosphoSitePlus
	N330	N-Glycosylation		score2	GlyGen UniProt	19159218
	C334	Methylation		score1	IEDB	31844290
	Y393	Phosphorylation		score1	UniProt	24275569
	V458	Phosphorylation		score1	UniProt	24275569
	S481	O-Glycosylation		score1	GlyGen	25813380
	T493	Phosphorylation		score1	UniProt	24275569

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	K184	Ubiquitination		score1	PhosphoSitePlus
	K288	Ubiquitination		score1	PhosphoSitePlus
	T378	Phosphorylation		score1	PhosphoSitePlus
	S385	Phosphorylation		score1	PhosphoSitePlus
	Y446	Phosphorylation		score1	PhosphoSitePlus
	S476	Phosphorylation		score1	PhosphoSitePlus
	K478	Ubiquitination		score1	PhosphoSitePlus
	K479	Ubiquitination		score1	PhosphoSitePlus
	K484	Ubiquitination		score1	PhosphoSitePlus
	Y490	Phosphorylation		score2	HPRD PhosphoSitePlus	19901323
	S491	Phosphorylation		score2	HPRD PhosphoSitePlus	20166139
	S493	Phosphorylation		score2	HPRD PhosphoSitePlus	20166139
	T496	Phosphorylation		score2	HPRD PhosphoSitePlus	20166139
	K500	Ubiquitination		score1	PhosphoSitePlus
	S502	Phosphorylation		score1	PhosphoSitePlus
	K508	Ubiquitination		score1	PhosphoSitePlus

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S487	Phosphorylation		score1	PhosphoSitePlus

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
K184	R184	Biomuta		DOID:3571 / liver cancer [ cosmic ]
K184	E184	Biomuta		DOID:1324 / lung cancer [ cosmic ]
N227	S227	Biomuta		DOID:9256 / colorectal cancer [ cosmic ]
N330	I330	Biomuta		DOID:4159 / skin cancer [ cosmic ]
N330	S330	Biomuta		DOID:4362 / cervical cancer [ icgc ]
C334	Y334	Biomuta		DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
C334	S334	Biomuta		DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
T378	M378	Biomuta		DOID:363 / uterine cancer [ icgc ]
Y446	*	Biomuta		DOID:3571 / liver cancer [ cosmic ]
K478	E478	Biomuta		DOID:1324 / lung cancer [ cosmic ]
S481	L481	Biomuta		DOID:363 / uterine cancer [ cosmic, icgc ]
S493	F493	Biomuta		DOID:1612 / breast cancer [ cosmic, icgc ]
S502	P502	Biomuta		DOID:9256 / colorectal cancer [ cosmic, icgc ]