Protein Information

Cytoscape View

UniProt AC / UniProt ID Q8WTS6 / SETD7_HUMAN
Protein Name Histone-lysine N-methyltransferase SETD7
Gene Name Name: SETD7
Organism Homo sapiens (Human)

DAG View
PRO Name histone-lysine N-methyltransferase SETD7 (human)
Definition A histone-lysine N-methyltransferase SETD7 that is encoded in the genome of human.
Short Label hSETD7
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q8WTS6 (SETD7) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
S3 Phosphorylation PhosphoSitePlus
K45 Ubiquitination PhosphoSitePlus
K111 Ubiquitination PhosphoSitePlus
R152 Methylation PhosphoSitePlus
K158 Ubiquitination PhosphoSitePlus
S225 Phosphorylation PhosphoSitePlus
Y305 Phosphorylation PhosphoSitePlus
T332 Phosphorylation PhosphoSitePlus
S340 Phosphorylation PhosphoSitePlus
S345 Phosphorylation PhosphoSitePlus
K358 Ubiquitination PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S3 R3 Biomuta DOID:1909 / melanoma [ cosmic ]
S340 R340 Biomuta DOID:3571 / liver cancer [ icgc ]