iPTMnet Report for Q8WTS6 (SETD7)
Protein Information
UniProt AC / UniProt ID | Q8WTS6 / SETD7_HUMAN |
Protein Name | Histone-lysine N-methyltransferase SETD7 |
Gene Name | Name: SETD7 Synonyms:KIAA1717,KMT7,SET7,SET9; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8WTS6 |
PRO Name | histone-lysine N-methyltransferase SETD7 (human) |
Definition | A histone-lysine N-methyltransferase SETD7 that is encoded in the genome of human. |
Short Label | hSETD7 |
Category | organism-gene |
Q8WTS6 (SETD7) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S3 | Phosphorylation | score1 | PhosphoSitePlus | |||
K45 | Ubiquitination | score1 | PhosphoSitePlus | |||
K111 | Ubiquitination | score1 | PhosphoSitePlus | |||
R152 | Methylation | score1 | PhosphoSitePlus | |||
K158 | Ubiquitination | score1 | PhosphoSitePlus | |||
S225 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y305 | Phosphorylation | score1 | PhosphoSitePlus | |||
T332 | Phosphorylation | score1 | PhosphoSitePlus | |||
S340 | Phosphorylation | score1 | PhosphoSitePlus | |||
S345 | Phosphorylation | score1 | PhosphoSitePlus | |||
K358 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S3 | R3 | Biomuta | DOID:1909 / melanoma [ cosmic ] | |
S340 | R340 | Biomuta | DOID:3571 / liver cancer [ icgc ] |