iPTMnet Report for Q8WTS6 (SETD7)
Protein Information
| UniProt AC / UniProt ID | Q8WTS6 / SETD7_HUMAN |
| Protein Name | Histone-lysine N-methyltransferase SETD7 |
| Gene Name | Name: SETD7 Synonyms:KIAA1717,KMT7,SET7; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8WTS6 |
| PRO Name | histone-lysine N-methyltransferase SETD7 (human) |
| Definition | A histone-lysine N-methyltransferase SETD7 that is encoded in the genome of human. |
| Short Label | hSETD7 |
| Category | organism-gene |
DAG ViewQ8WTS6 (SETD7) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S3 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C26 | Methylation | score1 | IEDB | 31844290 | ||
| Y30 | Phosphorylation | score1 | IEDB | 32387766 | ||
| K45 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K111 | Ubiquitination | score1 | PhosphoSitePlus | |||
| R152 | Methylation | score1 | PhosphoSitePlus | |||
| K158 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S225 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y305 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T332 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S340 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S345 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K358 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S3 | R3 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| T332 | I332 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |
