iPTMnet Report for Q8WTP8 (AEN)
Protein Information
| UniProt AC / UniProt ID | Q8WTP8 / AEN_HUMAN |
| Protein Name | Apoptosis-enhancing nuclease |
| Gene Name | Name: AEN Synonyms:ISG20L1;ORFNames:SBBI58; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8WTP8 |
| PRO Name | apoptosis-enhancing nuclease (human) |
| Definition | An apoptosis-enhancing nuclease that is encoded in the genome of human. |
| Short Label | hAEN |
| Category | organism-gene |
DAG ViewQ8WTP8 (AEN) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| C12 | Methylation | score1 | IEDB | 31844290 | ||
| K101 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K109 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T120 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C132 | Methylation | score1 | IEDB | 31844290 | ||
| K170 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K235 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K245 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S280 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T283 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T120 | M120 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] | |
| S280 | N280 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic ] |
