iPTMnet Report for Q8VDQ8 (Sirt2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8VDQ8 / SIR2_MOUSE
Protein Name NAD-dependent protein deacetylase sirtuin-2
Gene Name Name: Sirt2
Synonyms:Sir2l2;
Organism Mus musculus (Mouse)

PRO ID PR:Q8VDQ8
DAG View
PRO Name NAD-dependent protein deacetylase sirtuin-2 (mouse)
Definition An NAD-dependent protein deacetylase sirtuin-2 that is encoded in the genome of mouse.
Short Label mSIRT2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8VDQ8 (Sirt2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S23 Phosphorylation PhosphoSitePlus   UniProt 21183079
S25 Phosphorylation PhosphoSitePlus   UniProt 21183079
T27 Phosphorylation PhosphoSitePlus   UniProt 21183079
S53 Phosphorylation PhosphoSitePlus
K55 Ubiquitination PhosphoSitePlus
R75 Methylation PhosphoSitePlus
R77 Methylation PhosphoSitePlus
K126 Acetylation PhosphoSitePlus
K126 Ubiquitination PhosphoSitePlus
K144 Ubiquitination PhosphoSitePlus
K202 Ubiquitination PhosphoSitePlus
K210 Ubiquitination PhosphoSitePlus
K287 Ubiquitination PhosphoSitePlus
K312 Ubiquitination PhosphoSitePlus
K338 Acetylation PhosphoSitePlus
K338 Ubiquitination PhosphoSitePlus
K339 Ubiquitination PhosphoSitePlus
S356 Phosphorylation PhosphoSitePlus
S358 Phosphorylation PhosphoSitePlus
S364 Phosphorylation PhosphoSitePlus
T365 O-Glycosylation GlyGen 32848054
T365 Phosphorylation PhosphoSitePlus
T366 O-Glycosylation GlyGen   PhosphoSitePlus 22517741, 22645316, 32848054
T366 Phosphorylation PhosphoSitePlus
S368 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 21183079, 29158185
K371 Ubiquitination PhosphoSitePlus
S372 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 21183079, 29158185