iPTMnet Report for Q8TF61 (FBXO41)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8TF61 / FBX41_HUMAN
Protein Name F-box only protein 41
Gene Name Name: FBXO41
Synonyms:FBX41,KIAA1940;
Organism Homo sapiens (Human)

PRO ID PR:Q8TF61
DAG View
PRO Name F-box only protein 41 (human)
Definition An F-box only protein 41 that is encoded in the genome of human.
Short Label hFBXO41
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8TF61 (FBXO41) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S21 Phosphorylation PhosphoSitePlus
S23 Phosphorylation PhosphoSitePlus
S24 Phosphorylation PhosphoSitePlus
T37 Phosphorylation PhosphoSitePlus
K212 Ubiquitination PhosphoSitePlus
K229 Ubiquitination PhosphoSitePlus
K244 Ubiquitination PhosphoSitePlus
K293 Ubiquitination PhosphoSitePlus
K312 Ubiquitination PhosphoSitePlus
R360 Methylation PhosphoSitePlus
R372 Methylation PhosphoSitePlus
T389 Phosphorylation PhosphoSitePlus
Y390 Phosphorylation PhosphoSitePlus
S478 Phosphorylation PhosphoSitePlus
T479 Phosphorylation PhosphoSitePlus
S487 Phosphorylation PhosphoSitePlus
R530 Methylation PhosphoSitePlus
S538 Phosphorylation PhosphoSitePlus
S542 Phosphorylation PhosphoSitePlus
S547 Phosphorylation PhosphoSitePlus
S632 Phosphorylation PhosphoSitePlus
Y636 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S23 P23 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
K244 T244 Biomuta DOID:10534 / stomach cancer [ cosmic ]
R360 S360 Biomuta DOID:10534 / stomach cancer [ cosmic ]
R360 P360 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
R372 W372 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y390 N390 Biomuta DOID:4159 / skin cancer [ cosmic ]
R530 Q530 Biomuta DOID:4159 / skin cancer [ cosmic ]
R530 W530 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ]
Y636 H636 Biomuta DOID:9256 / colorectal cancer [ cosmic ]