iPTMnet Report for Q8TF44 (C2CD4C)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8TF44 / C2C4C_HUMAN
Protein Name C2 calcium-dependent domain-containing protein 4C
Gene Name Name: C2CD4C
Synonyms:FAM148C,KIAA1957,NLF3;
Organism Homo sapiens (Human)

PRO ID PR:Q8TF44
DAG View
PRO Name C2 calcium-dependent domain-containing protein 4C (human)
Definition A C2 calcium-dependent domain-containing protein 4C that is encoded in the genome of human.
Short Label hC2CD4C
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8TF44 (C2CD4C) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R22 Methylation PhosphoSitePlus
S33 Phosphorylation PhosphoSitePlus
T86 Phosphorylation PhosphoSitePlus
S89 Phosphorylation PhosphoSitePlus
T146 Phosphorylation PhosphoSitePlus
Y148 Phosphorylation PhosphoSitePlus
S156 Phosphorylation phospho.ELM   PhosphoSitePlus 18220336
S178 Phosphorylation PhosphoSitePlus
S206 O-Glycosylation GlyGen 29237092
S206 Phosphorylation PhosphoSitePlus
S229 Phosphorylation PhosphoSitePlus
S237 Phosphorylation PhosphoSitePlus
K240 Methylation PhosphoSitePlus
S256 Phosphorylation PhosphoSitePlus
S262 Phosphorylation PhosphoSitePlus
S264 Phosphorylation PhosphoSitePlus
S273 Phosphorylation PhosphoSitePlus   UniProt 21406692
T405 Phosphorylation PhosphoSitePlus
T415 Phosphorylation PhosphoSitePlus
S416 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R22 W22 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic ]
Y148 * Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S264 C264 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S416 Y416 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]