iPTMnet Report for Q8TF17 (SH3TC2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8TF17 / S3TC2_HUMAN
Protein Name SH3 domain and tetratricopeptide repeat-containing protein 2
Gene Name Name: SH3TC2
Synonyms:KIAA1985;ORFNames:PP12494;
Organism Homo sapiens (Human)

PRO ID PR:Q8TF17
DAG View
PRO Name SH3 domain and tetratricopeptide repeat-containing protein 2 (human)
Definition An SH3 domain and tetratricopeptide repeat-containing protein 2 that is encoded in the genome of human.
Short Label hSH3TC2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8TF17 (SH3TC2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T14 Phosphorylation PhosphoSitePlus
S101 Phosphorylation PhosphoSitePlus
S104 Phosphorylation PhosphoSitePlus
R529 Methylation PhosphoSitePlus
R605 Methylation PhosphoSitePlus
S958 Phosphorylation PhosphoSitePlus
Y1011 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S104 Phosphorylation HPRD 18691976
Site PTM Type PTM Enzyme Score Source PMID
T121 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T14 A14 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S101 I101 Biomuta DOID:1324 / lung cancer [ cosmic ]
R529 H529 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
R529 C529 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R605 H605 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S958 C958 Biomuta DOID:1324 / lung cancer [ cosmic ]