iPTMnet Report for Q8TEY7 (USP33)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8TEY7 / UBP33_HUMAN
Protein Name Ubiquitin carboxyl-terminal hydrolase 33
Gene Name Name: USP33
Synonyms:KIAA1097,VDU1;
Organism Homo sapiens (Human)

PRO ID PR:Q8TEY7
DAG View
PRO Name ubiquitin carboxyl-terminal hydrolase 33 (human)
Definition A ubiquitin carboxyl-terminal hydrolase 33 that is encoded in the genome of human.
Short Label hUSP33
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8TEY7 (USP33) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K50 Ubiquitination PhosphoSitePlus
K65 Ubiquitination PhosphoSitePlus
K126 Ubiquitination PhosphoSitePlus
S132 Phosphorylation PhosphoSitePlus
K151 Ubiquitination PhosphoSitePlus
T185 Phosphorylation PhosphoSitePlus
K230 Ubiquitination PhosphoSitePlus
K242 Acetylation PhosphoSitePlus
K258 Ubiquitination PhosphoSitePlus
S312 Phosphorylation PhosphoSitePlus
S314 Phosphorylation PhosphoSitePlus
S325 Phosphorylation PhosphoSitePlus
S327 Phosphorylation PhosphoSitePlus
K371 Ubiquitination PhosphoSitePlus
K374 Ubiquitination PhosphoSitePlus
S377 Phosphorylation PhosphoSitePlus   UniProt 24275569
K383 Ubiquitination PhosphoSitePlus
S387 Phosphorylation PhosphoSitePlus
K401 Ubiquitination PhosphoSitePlus
T422 Phosphorylation PhosphoSitePlus
S437 Phosphorylation PhosphoSitePlus
S439 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
K442 Ubiquitination PhosphoSitePlus
S443 Phosphorylation PhosphoSitePlus
S461 Phosphorylation PhosphoSitePlus
K512 Ubiquitination PhosphoSitePlus
K517 Ubiquitination PhosphoSitePlus
Y588 Phosphorylation PhosphoSitePlus
K617 Ubiquitination PhosphoSitePlus
T668 Phosphorylation PhosphoSitePlus
S670 Phosphorylation PhosphoSitePlus
S671 Phosphorylation PhosphoSitePlus
K714 Acetylation PhosphoSitePlus
S727 Phosphorylation PhosphoSitePlus
S736 Phosphorylation PhosphoSitePlus
Y741 Phosphorylation PhosphoSitePlus
S743 Phosphorylation PhosphoSitePlus
K877 Ubiquitination PhosphoSitePlus
K882 Ubiquitination PhosphoSitePlus
S907 Phosphorylation PhosphoSitePlus
Y909 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S439 Phosphorylation HPRD 18669648
Site PTM Type PTM Enzyme Score Source PMID
S408 Phosphorylation HPRD 18669648
Site PTM Type PTM Enzyme Score Source PMID
S439 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S314 L314 Biomuta DOID:363 / uterine cancer [ icgc ]
S327 I327 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S387 C387 Biomuta DOID:1612 / breast cancer [ icgc ] DOID:1324 / lung cancer [ cosmic ]
K401 E401 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S437 L437 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S443 L443 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S461 P461 Biomuta DOID:263 / kidney cancer [ cosmic ]
K517 N517 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S670 R670 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
S671 G671 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S671 R671 Biomuta DOID:4159 / skin cancer [ cosmic ]
K714 T714 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K882 I882 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc ]