iPTMnet Report for Q8TEY5 (CREB3L4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8TEY5 / CR3L4_HUMAN
Protein Name Cyclic AMP-responsive element-binding protein 3-like protein 4
Gene Name Name: CREB3L4
Synonyms:AIBZIP,CREB4,JAL;
Organism Homo sapiens (Human)

PRO ID PR:Q8TEY5
DAG View
PRO Name cyclic AMP-responsive element-binding protein 3-like protein 4 (human)
Definition A cyclic AMP-responsive element-binding protein 3-like protein 4 that is encoded in the genome of human.
Short Label hCREB3L4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8TEY5 (CREB3L4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K51 Ubiquitination PhosphoSitePlus
S63 Phosphorylation PhosphoSitePlus
S100 Phosphorylation PhosphoSitePlus
S109 Phosphorylation PhosphoSitePlus
Y117 Phosphorylation PhosphoSitePlus
C178 Methylation IEDB 31844290
K194 Ubiquitination PhosphoSitePlus
S203 Phosphorylation PhosphoSitePlus
K212 Ubiquitination PhosphoSitePlus
K239 Ubiquitination PhosphoSitePlus
K261 Ubiquitination PhosphoSitePlus
K262 Ubiquitination PhosphoSitePlus
T333 O-Glycosylation GlyGen 25813380
T339 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
K341 Ubiquitination PhosphoSitePlus
T344 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
T349 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
S354 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
S368 Phosphorylation PhosphoSitePlus
T369 Phosphorylation PhosphoSitePlus
K375 Acetylation PhosphoSitePlus
S388 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
C178 F178 Biomuta DOID:3571 / liver cancer [ cosmic ]
K239 E239 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:3571 / liver cancer [ cosmic ]
K239 T239 Biomuta DOID:9256 / colorectal cancer [ icgc ]
S368 L368 Biomuta DOID:1324 / lung cancer [ cosmic ]
T369 A369 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K375 T375 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]