iPTMnet Report for Q8TEX9 (IPO4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8TEX9 / IPO4_HUMAN
Protein Name Importin-4
Gene Name Name: IPO4
Synonyms:IMP4B,RANBP4;
Organism Homo sapiens (Human)

PRO ID PR:Q8TEX9
DAG View
PRO Name importin-4 (human)
Definition An importin-4 that is encoded in the genome of human.
Short Label hIPO4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8TEX9 (IPO4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 19413330, 22814378, 22223895
T18 Phosphorylation PhosphoSitePlus
C42 S-Nitrosylation dbSNO 19483679
S79 Phosphorylation PhosphoSitePlus
K81 Ubiquitination PhosphoSitePlus
T86 Phosphorylation phospho.ELM   PhosphoSitePlus 16964243
C95 Methylation IEDB 31844290
S173 Phosphorylation PhosphoSitePlus
K370 Ubiquitination PhosphoSitePlus
K401 Ubiquitination PhosphoSitePlus
K445 Ubiquitination PhosphoSitePlus
K457 Ubiquitination PhosphoSitePlus
T586 Phosphorylation PhosphoSitePlus
C708 S-Nitrosylation dbSNO 19483679
K715 Ubiquitination PhosphoSitePlus
K730 Ubiquitination PhosphoSitePlus
S754 Phosphorylation PhosphoSitePlus
Y755 Phosphorylation PhosphoSitePlus
K788 Ubiquitination PhosphoSitePlus
K801 Ubiquitination PhosphoSitePlus
T813 Phosphorylation PhosphoSitePlus
K865 Ubiquitination PhosphoSitePlus
K867 Ubiquitination PhosphoSitePlus
K875 Ubiquitination PhosphoSitePlus
S972 Phosphorylation PhosphoSitePlus
S1028 Phosphorylation PhosphoSitePlus
S1081 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T86 Phosphorylation HPRD 16964243


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K401 N401 Biomuta DOID:1324 / lung cancer [ cosmic ]
K445 N445 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K457 R457 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
C708 Y708 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
C708 F708 Biomuta DOID:1324 / lung cancer [ cosmic ]