iPTMnet Report for Q8TEW8 (PARD3B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8TEW8 / PAR3L_HUMAN
Protein Name Partitioning defective 3 homolog B
Gene Name Name: PARD3B
Synonyms:ALS2CR19,PAR3B,PAR3L;
Organism Homo sapiens (Human)

PRO ID PR:Q8TEW8
DAG View
PRO Name partitioning defective 3 homolog B (human)
Definition A partitioning defective 3 homolog B that is encoded in the genome of human.
Short Label hPARD3B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8TEW8 (PARD3B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K74 Acetylation PhosphoSitePlus
S90 Phosphorylation PhosphoSitePlus
S100 Phosphorylation PhosphoSitePlus   UniProt 24275569
T133 Phosphorylation PhosphoSitePlus
S140 Phosphorylation PhosphoSitePlus
S141 Phosphorylation PhosphoSitePlus
T193 Phosphorylation PhosphoSitePlus
T203 Phosphorylation PhosphoSitePlus
S207 Phosphorylation PhosphoSitePlus
S338 Phosphorylation PhosphoSitePlus
S346 Phosphorylation PhosphoSitePlus
S352 Phosphorylation PhosphoSitePlus   UniProt 23186163
S363 Phosphorylation PhosphoSitePlus
S364 Phosphorylation PhosphoSitePlus
S368 Phosphorylation PhosphoSitePlus   UniProt 23186163
S375 Phosphorylation PhosphoSitePlus
T442 Phosphorylation PhosphoSitePlus
T445 Phosphorylation PhosphoSitePlus
T456 Phosphorylation PhosphoSitePlus
K514 Methylation PhosphoSitePlus
K517 Methylation PhosphoSitePlus
K561 Ubiquitination PhosphoSitePlus
S575 Phosphorylation PhosphoSitePlus
T695 Phosphorylation PhosphoSitePlus
S710 Phosphorylation PhosphoSitePlus
S728 Phosphorylation PhosphoSitePlus
S730 Phosphorylation PhosphoSitePlus
S744 Phosphorylation PhosphoSitePlus
S745 Phosphorylation PhosphoSitePlus
S746 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163
S749 Phosphorylation PhosphoSitePlus
S780 Phosphorylation PhosphoSitePlus
S801 Phosphorylation PhosphoSitePlus   UniProt 21406692
K844 Acetylation PhosphoSitePlus
K848 Acetylation PhosphoSitePlus
K850 Acetylation PhosphoSitePlus
K852 Acetylation PhosphoSitePlus
K854 Acetylation PhosphoSitePlus
K869 Methylation PhosphoSitePlus
K870 Methylation PhosphoSitePlus
K885 Acetylation PhosphoSitePlus
K892 Acetylation PhosphoSitePlus
Y953 Phosphorylation PhosphoSitePlus
S973 Phosphorylation PhosphoSitePlus
S990 Phosphorylation PhosphoSitePlus
Y1000 Phosphorylation phospho.ELM   PhosphoSitePlus 18083107
Y1007 Phosphorylation PhosphoSitePlus
Y1033 Phosphorylation PhosphoSitePlus
Y1044 Phosphorylation PhosphoSitePlus
S1054 Phosphorylation PhosphoSitePlus
Y1056 Phosphorylation PhosphoSitePlus
Y1082 Phosphorylation PhosphoSitePlus
S1084 Phosphorylation PhosphoSitePlus
R1087 Methylation PhosphoSitePlus
Y1096 Phosphorylation PhosphoSitePlus
S1162 Phosphorylation PhosphoSitePlus
Y1172 Phosphorylation PhosphoSitePlus
R1181 Methylation PhosphoSitePlus
S1184 Phosphorylation PhosphoSitePlus   UniProt 24275569
Y1190 Phosphorylation PhosphoSitePlus
R1191 Methylation PhosphoSitePlus
T1192 Phosphorylation PhosphoSitePlus
S1195 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y938 Phosphorylation HPRD 18083107
Site PTM Type PTM Enzyme Score Source PMID
T918 Phosphorylation PhosphoSitePlus
S921 Phosphorylation PhosphoSitePlus
T922 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y931 Phosphorylation HPRD 18083107


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S90 N90 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S100 N100 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S141 R141 Biomuta DOID:9256 / colorectal cancer [ icgc ]
T193 N193 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S207 Y207 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S346 F346 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S364 Y364 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S368 * Biomuta DOID:4159 / skin cancer [ cosmic ]
S375 N375 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
K561 N561 Biomuta DOID:3571 / liver cancer [ cosmic ]
S575 C575 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S710 I710 Biomuta DOID:3571 / liver cancer [ cosmic ]
S728 P728 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S730 T730 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S746 F746 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S780 C780 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T918 M918 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic ]
Y1082 C1082 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y1082 * Biomuta DOID:1612 / breast cancer [ cosmic ]
Y1172 C1172 Biomuta DOID:10534 / stomach cancer [ cosmic ]
R1181 C1181 Biomuta DOID:4159 / skin cancer [ cosmic ]
R1181 L1181 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
R1181 H1181 Biomuta [ cosmic ] DOID:1612 / breast cancer [ cosmic ]
R1191 * Biomuta DOID:1612 / breast cancer [ cosmic ]
R1191 Q1191 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]