iPTMnet Report for Q8TEQ6 (GEMIN5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8TEQ6 / GEMI5_HUMAN
Protein Name Gem-associated protein 5
Gene Name Name: GEMIN5
Organism Homo sapiens (Human)

PRO ID PR:Q8TEQ6
DAG View
PRO Name gem-associated protein 5 (human)
Definition A gem-associated protein 5 that is encoded in the genome of human.
Short Label hGEMIN5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8TEQ6 (GEMIN5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S48 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18691976, 23186163
T51 Phosphorylation PhosphoSitePlus   UniProt 23186163
K122 Ubiquitination PhosphoSitePlus
S127 Phosphorylation PhosphoSitePlus
C240 Methylation IEDB 31844290
K247 Ubiquitination PhosphoSitePlus
R260 Methylation PhosphoSitePlus
R273 Methylation PhosphoSitePlus
K282 Ubiquitination PhosphoSitePlus
T345 Phosphorylation PhosphoSitePlus
K413 Ubiquitination PhosphoSitePlus
K419 Ubiquitination PhosphoSitePlus
T437 Phosphorylation PhosphoSitePlus
K450 Ubiquitination PhosphoSitePlus
K460 Ubiquitination PhosphoSitePlus
K470 Ubiquitination PhosphoSitePlus
Y474 Phosphorylation PhosphoSitePlus
S516 Phosphorylation PhosphoSitePlus
K524 Ubiquitination PhosphoSitePlus
K535 Ubiquitination PhosphoSitePlus
T616 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...28510447, 34019948, 30379171, 34725712, 30059200, 35254053, 35132862, 35083852, 32119511, 30620550, 28657654
S620 O-Glycosylation GlyGen 23301498, 33214551, 32938750, ...34019948, 30379171, 34725712, 28510447, 30059200, 35254053, 35132862, 35083852, 32119511, 30620550, 28657654
S624 O-Glycosylation GlyGen 23301498, 33214551, 28510447, ...34019948, 30379171, 34725712, 30059200, 35254053, 35132862, 35083852, 32119511, 30620550, 28657654
S624 Phosphorylation PhosphoSitePlus   UniProt 23186163
K724 Ubiquitination PhosphoSitePlus
S726 Phosphorylation PhosphoSitePlus
S735 Phosphorylation PhosphoSitePlus
T748 Phosphorylation HPRD   PhosphoSitePlus 18691976
T751 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18691976
K754 Acetylation PhosphoSitePlus
K754 Sumoylation PhosphoSitePlus
K754 Ubiquitination PhosphoSitePlus
S757 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163
S765 Phosphorylation PhosphoSitePlus
S770 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18691976
S778 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 21406692, 23186163, ...17081983, 15302935, 19664994, 19691289, 18452278, 19651622, 20068231
C793 Methylation IEDB 31844290
T807 O-Glycosylation GlyGen 23301498, 33214551, 28510447, ...34019948, 30379171, 34725712, 30059200, 35254053, 35132862, 35083852, 32119511, 30620550, 28657654
T807 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18691976, 16964243
S810 O-Glycosylation GlyGen 23301498, 33214551, 28510447, ...34019948, 30379171, 34725712, 30059200, 35254053, 35132862, 35083852, 32119511, 30620550, 28657654
K815 Methylation PhosphoSitePlus
T838 Phosphorylation PhosphoSitePlus
S847 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18691976
S852 Phosphorylation PhosphoSitePlus
T853 Phosphorylation HPRD   PhosphoSitePlus 18491316
S854 Phosphorylation HPRD   PhosphoSitePlus 18491316
K860 Ubiquitination PhosphoSitePlus
T897 Phosphorylation PhosphoSitePlus
K911 Acetylation PhosphoSitePlus
K933 Ubiquitination PhosphoSitePlus
K1012 Ubiquitination PhosphoSitePlus
Y1026 Phosphorylation PhosphoSitePlus
Y1039 Phosphorylation PhosphoSitePlus
Y1053 Phosphorylation PhosphoSitePlus
K1165 Ubiquitination PhosphoSitePlus
K1182 Ubiquitination PhosphoSitePlus
K1187 Ubiquitination PhosphoSitePlus
C1205 Methylation IEDB 31844290
C1255 Methylation IEDB 31844290
S1267 Phosphorylation PhosphoSitePlus
T1270 Phosphorylation PhosphoSitePlus
S1311 Phosphorylation PhosphoSitePlus
T1320 Phosphorylation HPRD   phospho.ELM 18669648
T1326 Phosphorylation HPRD   PhosphoSitePlus 18691976
T1330 Phosphorylation HPRD   phospho.ELM 18691976, 18669648
S1331 Phosphorylation PhosphoSitePlus
S1354 Phosphorylation PhosphoSitePlus
T1355 Phosphorylation PhosphoSitePlus
S1361 Phosphorylation PhosphoSitePlus
K1363 Acetylation PhosphoSitePlus
K1363 Ubiquitination PhosphoSitePlus
K1390 Ubiquitination PhosphoSitePlus
S1391 Phosphorylation HPRD   PhosphoSitePlus 18077418
S1416 Phosphorylation PhosphoSitePlus
K1425 Ubiquitination PhosphoSitePlus
K1436 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S48 R48 Biomuta DOID:363 / uterine cancer [ icgc ]
R260 * Biomuta [ cosmic ]
K419 N419 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K460 R460 Biomuta DOID:263 / kidney cancer [ cosmic ]
S624 F624 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S726 R726 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T751 I751 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S757 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S757 L757 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic, icgc ]
S765 N765 Biomuta DOID:1324 / lung cancer [ cosmic ]
S810 F810 Biomuta DOID:363 / uterine cancer [ icgc ]
K1012 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S1267 F1267 Biomuta DOID:1324 / lung cancer [ cosmic ]
S1311 Y1311 Biomuta DOID:3571 / liver cancer [ cosmic ]
T1326 M1326 Biomuta DOID:9253 / gastrointestinal stromal tumor [ cosmic ]
S1361 L1361 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1416 I1416 Biomuta DOID:1319 / brain cancer [ cosmic ]
S1416 R1416 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
K1425 R1425 Biomuta DOID:9256 / colorectal cancer [ cosmic ]