iPTMnet Report for Q8TEP8 (CEP192)
Protein Information
UniProt AC / UniProt ID | Q8TEP8 / CE192_HUMAN |
Protein Name | Centrosomal protein of 192 kDa |
Gene Name | Name: CEP192 Synonyms:KIAA1569;ORFNames:PP8407; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8TEP8 |
PRO Name | centrosomal protein of 192 kDa (human) |
Definition | A centrosomal protein of 192 kDa that is encoded in the genome of human. |
Short Label | hCEP192 |
Category | organism-gene |
Q8TEP8 (CEP192) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T44 | Phosphorylation | P53350 (PLK1) | score3 | PhosphoSitePlus Signor | 26012549 | |
S92 | Phosphorylation | score1 | PhosphoSitePlus | |||
S98 | Phosphorylation | score1 | PhosphoSitePlus | |||
K103 | Ubiquitination | score1 | PhosphoSitePlus | |||
S104 | Phosphorylation | score1 | PhosphoSitePlus | |||
S112 | Phosphorylation | score1 | PhosphoSitePlus | |||
K117 | Ubiquitination | score1 | PhosphoSitePlus | |||
S157 | Phosphorylation | score1 | PhosphoSitePlus | |||
K170 | Ubiquitination | score1 | PhosphoSitePlus | |||
K173 | Ubiquitination | score1 | PhosphoSitePlus | |||
K181 | Acetylation | score1 | PhosphoSitePlus | |||
K181 | Ubiquitination | score1 | PhosphoSitePlus | |||
K186 | Ubiquitination | score1 | PhosphoSitePlus | |||
K189 | Ubiquitination | score1 | PhosphoSitePlus | |||
S193 | Phosphorylation | score1 | PhosphoSitePlus | |||
T195 | Phosphorylation | score1 | PhosphoSitePlus | |||
S196 | Phosphorylation | score1 | PhosphoSitePlus | |||
S269 | Phosphorylation | score1 | PhosphoSitePlus | |||
S329 | Phosphorylation | score1 | PhosphoSitePlus | |||
K336 | Ubiquitination | score1 | PhosphoSitePlus | |||
K342 | Ubiquitination | score1 | PhosphoSitePlus | |||
K355 | Ubiquitination | score1 | PhosphoSitePlus | |||
K360 | Ubiquitination | score1 | PhosphoSitePlus | |||
T361 | Phosphorylation | score1 | PhosphoSitePlus | |||
K368 | Ubiquitination | score1 | PhosphoSitePlus | |||
T387 | Phosphorylation | score1 | PhosphoSitePlus | |||
K391 | Ubiquitination | score1 | PhosphoSitePlus | |||
S457 | Phosphorylation | score1 | PhosphoSitePlus | |||
K464 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y486 | Phosphorylation | score1 | PhosphoSitePlus | |||
S499 | Phosphorylation | score1 | PhosphoSitePlus | |||
S501 | Phosphorylation | score1 | PhosphoSitePlus | |||
S563 | Phosphorylation | score1 | PhosphoSitePlus | |||
S565 | Phosphorylation | score1 | PhosphoSitePlus | |||
K571 | Ubiquitination | score1 | PhosphoSitePlus | |||
S580 | Phosphorylation | score1 | PhosphoSitePlus | |||
K602 | Ubiquitination | score1 | PhosphoSitePlus | |||
S605 | Phosphorylation | score1 | PhosphoSitePlus | |||
S612 | Phosphorylation | score1 | PhosphoSitePlus | |||
K687 | Ubiquitination | score1 | PhosphoSitePlus | |||
K697 | Ubiquitination | score1 | PhosphoSitePlus | |||
K704 | Ubiquitination | score1 | PhosphoSitePlus | |||
K757 | Ubiquitination | score1 | PhosphoSitePlus | |||
K772 | Ubiquitination | score1 | PhosphoSitePlus | |||
S812 | Phosphorylation | score1 | UniProt | 20068231 | ||
K887 | Ubiquitination | score1 | PhosphoSitePlus | |||
K896 | Ubiquitination | score1 | PhosphoSitePlus | |||
K922 | Ubiquitination | score1 | PhosphoSitePlus | |||
S995 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1093 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1131 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1143 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1172 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1433 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1502 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1516 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1602 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1667 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1752 | Ubiquitination | score1 | PhosphoSitePlus | |||
S1755 | Phosphorylation | score1 | UniProt | 23186163, 20068231 | ||
K1890 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1942 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1975 | Ubiquitination | score1 | PhosphoSitePlus | |||
C2066 | Methylation | score1 | IEDB | 31844290 | ||
K2078 | Ubiquitination | score1 | PhosphoSitePlus | |||
S2098 | Phosphorylation | score1 | UniProt | 20068231 | ||
K2105 | Ubiquitination | score1 | PhosphoSitePlus | |||
S2110 | Phosphorylation | score1 | UniProt | 23186163, 20068231 | ||
K2244 | Ubiquitination | score1 | PhosphoSitePlus | |||
C2401 | Methylation | score1 | IEDB | 31844290 | ||
K2415 | Ubiquitination | score1 | PhosphoSitePlus | |||
S2472 | Phosphorylation | score1 | IEDB | 35494241 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S9 | Phosphorylation | score1 | PhosphoSitePlus | |||
S16 | Phosphorylation | score1 | PhosphoSitePlus | |||
K19 | Ubiquitination | score1 | PhosphoSitePlus | |||
S29 | Phosphorylation | score1 | PhosphoSitePlus | |||
S32 | Phosphorylation | score1 | PhosphoSitePlus | |||
K91 | Ubiquitination | score1 | PhosphoSitePlus | |||
K101 | Ubiquitination | score1 | PhosphoSitePlus | |||
S115 | Phosphorylation | score1 | PhosphoSitePlus | |||
S124 | Phosphorylation | score1 | PhosphoSitePlus | |||
T153 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y163 | Phosphorylation | score1 | PhosphoSitePlus | |||
S164 | Phosphorylation | score1 | PhosphoSitePlus | |||
K176 | Acetylation | score1 | PhosphoSitePlus | |||
K176 | Ubiquitination | score1 | PhosphoSitePlus | |||
S177 | Phosphorylation | score1 | PhosphoSitePlus | |||
S180 | Phosphorylation | score1 | PhosphoSitePlus | |||
K187 | Acetylation | score1 | PhosphoSitePlus | |||
S195 | Phosphorylation | score1 | PhosphoSitePlus | |||
S199 | Phosphorylation | score1 | PhosphoSitePlus | |||
S208 | Phosphorylation | score1 | PhosphoSitePlus | |||
S216 | Phosphorylation | score1 | PhosphoSitePlus | |||
K219 | Ubiquitination | score1 | PhosphoSitePlus | |||
S268 | Phosphorylation | score1 | PhosphoSitePlus | |||
S278 | Phosphorylation | score1 | PhosphoSitePlus | |||
K284 | Ubiquitination | score1 | PhosphoSitePlus | |||
S287 | Phosphorylation | score1 | PhosphoSitePlus | |||
K300 | Ubiquitination | score1 | PhosphoSitePlus | |||
S303 | Phosphorylation | score1 | PhosphoSitePlus | |||
T306 | Phosphorylation | score1 | PhosphoSitePlus | |||
T320 | Phosphorylation | score1 | PhosphoSitePlus | |||
S321 | Phosphorylation | score1 | PhosphoSitePlus | |||
S348 | Phosphorylation | score1 | PhosphoSitePlus | |||
S363 | Phosphorylation | score1 | PhosphoSitePlus | |||
S367 | Phosphorylation | score1 | PhosphoSitePlus | |||
S381 | Phosphorylation | score1 | PhosphoSitePlus | |||
S387 | Phosphorylation | score1 | PhosphoSitePlus | |||
S391 | Phosphorylation | score1 | PhosphoSitePlus | |||
S408 | Phosphorylation | score1 | PhosphoSitePlus | |||
S448 | Phosphorylation | score1 | PhosphoSitePlus | |||
S468 | Phosphorylation | score1 | PhosphoSitePlus | |||
S472 | Phosphorylation | score1 | PhosphoSitePlus | |||
T476 | Phosphorylation | score1 | PhosphoSitePlus | |||
S482 | Phosphorylation | score1 | PhosphoSitePlus | |||
S516 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y533 | Phosphorylation | score1 | PhosphoSitePlus | |||
K542 | Ubiquitination | score1 | PhosphoSitePlus | |||
S555 | Phosphorylation | score1 | PhosphoSitePlus | |||
K576 | Ubiquitination | score1 | PhosphoSitePlus | |||
S592 | Phosphorylation | score1 | PhosphoSitePlus | |||
S604 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y829 | Phosphorylation | score1 | PhosphoSitePlus | |||
T845 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1065 | Ubiquitination | score1 | PhosphoSitePlus | |||
S1155 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1159 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1190 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1263 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1294 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1330 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1339 | Acetylation | score1 | PhosphoSitePlus | |||
K1340 | Acetylation | score1 | PhosphoSitePlus | |||
K1346 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1358 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1379 | Ubiquitination | score1 | PhosphoSitePlus | |||
S1385 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1407 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1482 | Ubiquitination | score1 | PhosphoSitePlus | |||
S1484 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1494 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1496 | Ubiquitination | score1 | PhosphoSitePlus | |||
S1502 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1514 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1518 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1602 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1605 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1654 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1721 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1819 | Ubiquitination | score1 | PhosphoSitePlus | |||
T1855 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1856 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1862 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y1893 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y1900 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1911 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1923 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1928 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1940 | Ubiquitination | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T44 | Phosphorylation | P53350 (PLK1) | score2 | PhosphoSitePlus | 26012549 | |
S804 | Phosphorylation | score0 | HPRD | 20068231 | ||
S812 | Phosphorylation | score0 | HPRD | 20068231 | ||
S828 | Phosphorylation | score0 | HPRD | 20068231 | ||
S1751 | Phosphorylation | score0 | HPRD | 18669648, 20068231, 16565220 | ||
S1755 | Phosphorylation | score0 | HPRD | 18669648, 20068231, 16565220 | ||
S2098 | Phosphorylation | score0 | HPRD | 20068231 | ||
S2110 | Phosphorylation | score0 | HPRD | 19413330, 20068231 | ||
S2250 | Phosphorylation | score0 | HPRD | 20068231 | ||
T2458 | Phosphorylation | score0 | HPRD | 20068231 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S98 | Y98 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S269 | I269 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
K1502 | T1502 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
S2110 | F2110 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] |