iPTMnet Report for Q8TED9 (AFAP1L1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8TED9 / AF1L1_HUMAN
Protein Name Actin filament-associated protein 1-like 1
Gene Name Name: AFAP1L1
Organism Homo sapiens (Human)

PRO ID PR:Q8TED9
DAG View
PRO Name actin filament-associated protein 1-like 1 (human)
Definition An actin filament-associated protein 1-like 1 that is encoded in the genome of human.
Short Label hAFAP1L1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8TED9 (AFAP1L1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S43 Phosphorylation PhosphoSitePlus
S98 Phosphorylation PhosphoSitePlus
S104 Phosphorylation PhosphoSitePlus
Y126 Phosphorylation PhosphoSitePlus
Y158 Phosphorylation PhosphoSitePlus
Y159 Phosphorylation PhosphoSitePlus
S315 Phosphorylation PhosphoSitePlus
K316 Ubiquitination PhosphoSitePlus
S329 Phosphorylation PhosphoSitePlus
S349 Phosphorylation PhosphoSitePlus
S353 Phosphorylation PhosphoSitePlus
S361 Phosphorylation PhosphoSitePlus
K376 Methylation PhosphoSitePlus
S378 Phosphorylation PhosphoSitePlus
K383 Methylation PhosphoSitePlus
S385 Phosphorylation PhosphoSitePlus
T395 Phosphorylation PhosphoSitePlus
K441 Methylation PhosphoSitePlus
Y446 Phosphorylation PhosphoSitePlus
S513 Phosphorylation PhosphoSitePlus
T516 Phosphorylation PhosphoSitePlus
Y524 Phosphorylation PhosphoSitePlus
Y557 Phosphorylation PhosphoSitePlus
Y562 Phosphorylation PhosphoSitePlus
S583 Phosphorylation PhosphoSitePlus
S584 Phosphorylation PhosphoSitePlus
S586 Phosphorylation PhosphoSitePlus
S603 Phosphorylation PhosphoSitePlus
S745 Phosphorylation PhosphoSitePlus
S747 Phosphorylation PhosphoSitePlus
S751 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S713 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S98 N98 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
T395 A395 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
T516 N516 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
Y562 H562 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S584 F584 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S603 P603 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S713 N713 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]