Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8TED1 / GPX8_HUMAN
Protein Name Probable glutathione peroxidase 8
Gene Name Name: GPX8
ORFNames:UNQ847/PRO1785;
Organism Homo sapiens (Human)

PRO ID PR:Q8TED1
DAG View
PRO Name glutathione peroxidase 8 (human)
Definition A glutathione peroxidase 8 that is encoded in the genome of human.
Short Label hGPX8
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8TED1 (GPX8) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
K10 Ubiquitination PhosphoSitePlus
K53 Ubiquitination PhosphoSitePlus
S61 Phosphorylation PhosphoSitePlus
K64 Ubiquitination PhosphoSitePlus
K90 Ubiquitination PhosphoSitePlus
K94 Ubiquitination PhosphoSitePlus
K120 Ubiquitination PhosphoSitePlus
K128 Ubiquitination PhosphoSitePlus
K141 Ubiquitination PhosphoSitePlus
K159 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K53 T53 Biomuta DOID:1793 / pancreatic cancer [ icgc ]
S61 Y61 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:11054 / urinary bladder cancer [ tcga ]