iPTMnet Report for Q8TED1 (GPX8)
Protein Information
| UniProt AC / UniProt ID | Q8TED1 / GPX8_HUMAN |
| Protein Name | Probable glutathione peroxidase 8 |
| Gene Name | Name: GPX8 ORFNames:UNQ847/PRO1785; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8TED1 |
| PRO Name | probable glutathione peroxidase 8 (human) |
| Definition | A probable glutathione peroxidase 8 that is encoded in the genome of human. |
| Short Label | hGPX8 |
| Category | organism-gene |
DAG ViewQ8TED1 (GPX8) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| M1 | Acetylation | score1 | UniProt | 22814378 | ||
| K10 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K53 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S61 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K64 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K90 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K94 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K120 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K128 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T133 | O-Glycosylation | score1 | GlyGen | 35289036 | ||
| K141 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K159 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S61 | Y61 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
| S61 | F61 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| K159 | E159 | Biomuta | [ cosmic ] |
