Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8TEA8 / DTD1_HUMAN
Protein Name D-aminoacyl-tRNA deacylase 1
Gene Name Name: DTD1
Synonyms:C20orf88,DUEB,HARS2;
Organism Homo sapiens (Human)

PRO ID PR:Q8TEA8
DAG View
PRO Name D-aminoacyl-tRNA deacylase 1 (human)
Definition A D-aminoacyl-tRNA deacylase 1 that is encoded in the genome of human.
Short Label hDTD1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8TEA8 (DTD1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R53 Methylation PhosphoSitePlus
K61 Ubiquitination PhosphoSitePlus
K65 Acetylation PhosphoSitePlus
K123 Ubiquitination PhosphoSitePlus
S179 Phosphorylation PhosphoSitePlus
S181 Phosphorylation PhosphoSitePlus
S182 Phosphorylation PhosphoSitePlus
T187 Phosphorylation PhosphoSitePlus
S194 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 19413330, 18491316, 19651622, ...18669648, 20166139, 20068231
S196 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 19413330, 17287340, 18669648, ...18088087, 20068231
S197 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 21406692, 18491316, ...18088087, 19690332, 19651622, 18669648, 23186163, 19415658
S204 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 19413330, 17287340
S205 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 18088087, 19664994, ...18669648, 19690332
R207 Methylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R53 C53 Biomuta DOID:3070 / malignant glioma [ cosmic, icgc, tcga ]
R53 L53 Biomuta DOID:3571 / liver cancer [ icgc ]
R53 H53 Biomuta DOID:9256 / colorectal cancer [ tcga ] DOID:2531 / hematologic cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
K61 N61 Biomuta DOID:3571 / liver cancer [ icgc ]
S181 * Biomuta DOID:9256 / colorectal cancer [ tcga ] DOID:1909 / melanoma [ cosmic ]
S197 T197 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]