iPTMnet Report for Q8TE77 (SSH3)
Protein Information
| UniProt AC / UniProt ID | Q8TE77 / SSH3_HUMAN |
| Protein Name | Protein phosphatase Slingshot homolog 3 |
| Gene Name | Name: SSH3 Synonyms:SSH3L; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8TE77 |
| PRO Name | protein phosphatase Slingshot homolog 3 (human) |
| Definition | A protein phosphatase Slingshot homolog 3 that is encoded in the genome of human. |
| Short Label | hSSH3 |
| Category | organism-gene |
Q8TE77 (SSH3) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| T5 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S9 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163, 24275569 | ||
| S13 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S16 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T17 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S37 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 22267324, 18669648, 23186163, ... | ||
| S37 | Phosphorylation | Q96GD4 (AURKB) | score1 | PhosphoSitePlus | 22267324 | |
| K67 | Acetylation | score1 | PhosphoSitePlus | |||
| S70 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T79 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S85 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 17525332 | ||
| S87 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 17525332, 24275569 | ||
| K90 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S259 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K281 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S290 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T292 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S293 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K294 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S385 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S484 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K523 | Sumoylation | score1 | PhosphoSitePlus | |||
| S547 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K598 | Methylation | score1 | PhosphoSitePlus | |||
| S602 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T605 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S609 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S637 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T638 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S649 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648, 16964243 | ||
| S653 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S7 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S9 | Phosphorylation | score0 | HPRD | 20166139 | ||
| S37 | Phosphorylation | score0 | HPRD | 18212344, 18767875, 17322306, ... | ||
| S85 | Phosphorylation | score0 | HPRD | 17525332 | ||
| S87 | Phosphorylation | score0 | HPRD | 18691976, 17525332 | ||
| S609 | Phosphorylation | score0 | HPRD | 17924679 | ||
| S649 | Phosphorylation | score0 | HPRD | 18669648, 16964243 | ||
| S653 | Phosphorylation | score0 | HPRD | 18669648 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K67 | M67 | Biomuta | DOID:10283 / prostate cancer [ icgc ] | |
| T79 | I79 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| S85 | Y85 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| S85 | F85 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
| S293 | F293 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S385 | L385 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S547 | F547 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S637 | F637 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] |
DAG View