iPTMnet Report for Q8TE76 (MORC4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8TE76 / MORC4_HUMAN
Protein Name MORC family CW-type zinc finger protein 4
Gene Name Name: MORC4
Synonyms:ZCW4,ZCWCC2;
Organism Homo sapiens (Human)

PRO ID PR:Q8TE76
DAG View
PRO Name MORC family CW-type zinc finger protein 4 (human)
Definition A MORC family CW-type zinc finger protein 4 that is encoded in the genome of human.
Short Label hMORC4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8TE76 (MORC4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T87 Phosphorylation PhosphoSitePlus
T94 Phosphorylation PhosphoSitePlus
S114 Phosphorylation IEDB 35494241
K134 Ubiquitination PhosphoSitePlus
C272 Methylation IEDB 31844290
K308 Ubiquitination PhosphoSitePlus
K383 Ubiquitination PhosphoSitePlus
K403 Ubiquitination PhosphoSitePlus
S465 Phosphorylation PhosphoSitePlus
S532 Phosphorylation PhosphoSitePlus
K565 Sumoylation PhosphoSitePlus
K575 Ubiquitination PhosphoSitePlus
K614 Ubiquitination PhosphoSitePlus
S615 Phosphorylation PhosphoSitePlus
S617 Phosphorylation PhosphoSitePlus
S620 Phosphorylation PhosphoSitePlus
T621 Phosphorylation PhosphoSitePlus
Y646 Phosphorylation PhosphoSitePlus
S656 Phosphorylation PhosphoSitePlus
S704 Phosphorylation PhosphoSitePlus
K748 Ubiquitination PhosphoSitePlus
K792 Ubiquitination PhosphoSitePlus
K808 Ubiquitination PhosphoSitePlus
K843 Ubiquitination PhosphoSitePlus
K891 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S114 R114 Biomuta [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S114 I114 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
C272 S272 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
S465 Y465 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K614 I614 Biomuta DOID:3571 / liver cancer [ cosmic ]
S615 L615 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic ]
S620 N620 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y646 F646 Biomuta DOID:363 / uterine cancer [ icgc ]
S704 * Biomuta DOID:1324 / lung cancer [ cosmic ]