iPTMnet Report for Q8TE68 (EPS8L1)
Protein Information
UniProt AC / UniProt ID | Q8TE68 / ES8L1_HUMAN |
Protein Name | Epidermal growth factor receptor kinase substrate 8-like protein 1 |
Gene Name | Name: EPS8L1 Synonyms:DRC3,EPS8R1;ORFNames:PP10566; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8TE68 |
PRO Name | epidermal growth factor receptor kinase substrate 8-like protein 1 (human) |
Definition | An epidermal growth factor receptor kinase substrate 8-like protein 1 that is encoded in the genome of human. |
Short Label | hEPS8L1 |
Category | organism-gene |
Q8TE68 (EPS8L1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
Y19 | Phosphorylation | score1 | PhosphoSitePlus | |||
K61 | Ubiquitination | score1 | PhosphoSitePlus | |||
S116 | Phosphorylation | score1 | PhosphoSitePlus | |||
S118 | Phosphorylation | score1 | PhosphoSitePlus | |||
T173 | Phosphorylation | score1 | PhosphoSitePlus | |||
S182 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163 | ||
T187 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
S195 | Phosphorylation | score1 | PhosphoSitePlus | |||
S201 | Phosphorylation | score1 | PhosphoSitePlus | |||
T202 | Phosphorylation | score1 | PhosphoSitePlus | |||
S239 | Phosphorylation | score1 | PhosphoSitePlus | |||
T305 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y316 | Phosphorylation | score1 | PhosphoSitePlus | |||
S328 | Phosphorylation | score1 | PhosphoSitePlus | |||
S494 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y526 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y529 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y535 | Phosphorylation | score1 | PhosphoSitePlus | |||
S543 | Phosphorylation | score1 | PhosphoSitePlus | |||
S545 | Phosphorylation | score1 | PhosphoSitePlus | |||
S549 | Phosphorylation | score1 | PhosphoSitePlus | |||
S552 | Phosphorylation | score1 | PhosphoSitePlus | |||
T553 | Phosphorylation | score1 | PhosphoSitePlus | |||
S580 | Phosphorylation | score1 | PhosphoSitePlus | |||
S583 | Phosphorylation | score1 | PhosphoSitePlus | |||
S617 | Phosphorylation | score1 | PhosphoSitePlus | |||
S631 | Phosphorylation | score1 | PhosphoSitePlus | |||
S634 | Phosphorylation | score1 | PhosphoSitePlus | |||
T660 | Phosphorylation | score1 | PhosphoSitePlus | |||
S676 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y684 | Phosphorylation | score1 | PhosphoSitePlus | |||
S685 | Phosphorylation | score1 | PhosphoSitePlus | |||
T688 | Phosphorylation | score1 | PhosphoSitePlus | |||
K709 | Acetylation | score1 | PhosphoSitePlus | |||
K712 | Acetylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S55 | A55 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
T60 | S60 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
S118 | L118 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] | |
S182 | A182 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
T187 | S187 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
Y316 | C316 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
S545 | G545 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
S549 | I549 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S552 | R552 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
S631 | N631 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S676 | R676 | Biomuta | DOID:263 / kidney cancer [ cosmic ] | |
Y684 | C684 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |