iPTMnet Report for Q8TE68 (EPS8L1)
Protein Information
| UniProt AC / UniProt ID | Q8TE68 / ES8L1_HUMAN |
| Protein Name | Epidermal growth factor receptor kinase substrate 8-like protein 1 |
| Gene Name | Name: EPS8L1 Synonyms:DRC3,EPS8R1;ORFNames:PP10566; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8TE68 |
| PRO Name | epidermal growth factor receptor kinase substrate 8-like protein 1 (human) |
| Definition | An epidermal growth factor receptor kinase substrate 8-like protein 1 that is encoded in the genome of human. |
| Short Label | hEPS8L1 |
| Category | organism-gene |
Q8TE68 (EPS8L1) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| Y19 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K61 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S116 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S118 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T173 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S182 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163 | ||
| T187 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
| S195 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S201 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T202 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S239 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T305 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y316 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S328 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S494 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y526 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y529 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y535 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S543 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S545 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S549 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S552 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T553 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S580 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S583 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S617 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S631 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S634 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T660 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S676 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y684 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S685 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T688 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K709 | Acetylation | score1 | PhosphoSitePlus | |||
| K712 | Acetylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S55 | A55 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
| T60 | S60 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
| S118 | L118 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] | |
| S182 | A182 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
| T187 | S187 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
| Y316 | C316 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
| S545 | G545 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
| S549 | I549 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S552 | R552 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
| S631 | N631 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S676 | R676 | Biomuta | DOID:263 / kidney cancer [ cosmic ] | |
| Y684 | C684 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |
DAG View