iPTMnet Report for Q8TE67 (EPS8L3)
Protein Information
UniProt AC / UniProt ID | Q8TE67 / ES8L3_HUMAN |
Protein Name | Epidermal growth factor receptor kinase substrate 8-like protein 3 |
Gene Name | Name: EPS8L3 Synonyms:EPS8R3; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8TE67 |
PRO Name | epidermal growth factor receptor kinase substrate 8-like protein 3 (human) |
Definition | An epidermal growth factor receptor kinase substrate 8-like protein 3 that is encoded in the genome of human. |
Short Label | hEPS8L3 |
Category | organism-gene |
Q8TE67 (EPS8L3) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S2 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y10 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y16 | Phosphorylation | score1 | PhosphoSitePlus | |||
S17 | Phosphorylation | score1 | PhosphoSitePlus | |||
T21 | Phosphorylation | score1 | PhosphoSitePlus | |||
S201 | Phosphorylation | score1 | PhosphoSitePlus | |||
S205 | Phosphorylation | score1 | PhosphoSitePlus | |||
S214 | Phosphorylation | score1 | PhosphoSitePlus | |||
S231 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S320 | Phosphorylation | score1 | PhosphoSitePlus | |||
S415 | Phosphorylation | score1 | PhosphoSitePlus | |||
S420 | Phosphorylation | score1 | PhosphoSitePlus | |||
T421 | Phosphorylation | score1 | PhosphoSitePlus | |||
S441 | Phosphorylation | score1 | PhosphoSitePlus | |||
S445 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y459 | Phosphorylation | score1 | PhosphoSitePlus | |||
T555 | Phosphorylation | score1 | PhosphoSitePlus | |||
S557 | Phosphorylation | score1 | PhosphoSitePlus | |||
S580 | Phosphorylation | score1 | PhosphoSitePlus | |||
S592 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S154 | Phosphorylation | score1 | PhosphoSitePlus | |||
S232 | Phosphorylation | score0 | HPRD | 18452278 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S2 | P2 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S2 | L2 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ] | |
Y16 | H16 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
T21 | N21 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S154 | G154 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
S154 | N154 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S205 | F205 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
S214 | G214 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S320 | P320 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
S441 | T441 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S445 | I445 | Biomuta | DOID:3953 / adrenal gland cancer [ cosmic ] | |
S445 | N445 | Biomuta | DOID:1793 / pancreatic cancer [ icgc ] |