Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8TE67 / ES8L3_HUMAN
Protein Name Epidermal growth factor receptor kinase substrate 8-like protein 3
Gene Name Name: EPS8L3
Synonyms:EPS8R3;
Organism Homo sapiens (Human)

PRO ID PR:Q8TE67
DAG View
PRO Name epidermal growth factor receptor kinase substrate 8-like protein 3 (human)
Definition An epidermal growth factor receptor kinase substrate 8-like protein 3 that is encoded in the genome of human.
Short Label hEPS8L3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8TE67 (EPS8L3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation PhosphoSitePlus
Y10 Phosphorylation PhosphoSitePlus
Y16 Phosphorylation PhosphoSitePlus
S17 Phosphorylation PhosphoSitePlus
T21 Phosphorylation PhosphoSitePlus
S201 Phosphorylation PhosphoSitePlus
S205 Phosphorylation PhosphoSitePlus
S214 Phosphorylation PhosphoSitePlus
S231 Phosphorylation PhosphoSitePlus   UniProt 23186163
S320 Phosphorylation PhosphoSitePlus
S415 Phosphorylation PhosphoSitePlus
S420 Phosphorylation PhosphoSitePlus
T421 Phosphorylation PhosphoSitePlus
S441 Phosphorylation PhosphoSitePlus
S445 Phosphorylation PhosphoSitePlus
Y459 Phosphorylation PhosphoSitePlus
T555 Phosphorylation PhosphoSitePlus
S557 Phosphorylation PhosphoSitePlus
S580 Phosphorylation PhosphoSitePlus
S592 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S231 Phosphorylation HPRD 18452278
Site PTM Type PTM Enzyme Score Source PMID
S231 Phosphorylation HPRD 18452278
Site PTM Type PTM Enzyme Score Source PMID
S154 Phosphorylation PhosphoSitePlus
S232 Phosphorylation HPRD 18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S2 P2 Biomuta DOID:1324 / lung cancer [ tcga ]
S2 L2 Biomuta DOID:1324 / lung cancer [ tcga ] DOID:3070 / malignant glioma [ cosmic, icgc, tcga ]
Y16 H16 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
T21 N21 Biomuta DOID:1324 / lung cancer [ cosmic ]
S205 F205 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S214 G214 Biomuta DOID:1324 / lung cancer [ cosmic ]
S320 P320 Biomuta DOID:1612 / breast cancer [ cosmic, icgc, tcga ]
S445 N445 Biomuta DOID:1793 / pancreatic cancer [ tcga ]
T555 M555 Biomuta DOID:1324 / lung cancer [ tcga ]
S557 R557 Biomuta DOID:3571 / liver cancer [ icgc ]