iPTMnet Report for Q8TE67 (EPS8L3)
Protein Information
| UniProt AC / UniProt ID | Q8TE67 / ES8L3_HUMAN |
| Protein Name | Epidermal growth factor receptor kinase substrate 8-like protein 3 |
| Gene Name | Name: EPS8L3 Synonyms:EPS8R3; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8TE67 |
| PRO Name | epidermal growth factor receptor kinase substrate 8-like protein 3 (human) |
| Definition | An epidermal growth factor receptor kinase substrate 8-like protein 3 that is encoded in the genome of human. |
| Short Label | hEPS8L3 |
| Category | organism-gene |
Q8TE67 (EPS8L3) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S2 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y10 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y16 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S17 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T21 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S201 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S205 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S214 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S231 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| S320 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S415 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S420 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T421 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S441 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S445 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y459 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T555 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S557 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S580 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S592 | Phosphorylation | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S154 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S232 | Phosphorylation | score0 | HPRD | 18452278 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S2 | P2 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| S2 | L2 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ] | |
| Y16 | H16 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| T21 | N21 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S154 | G154 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| S154 | N154 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S205 | F205 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| S214 | G214 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S320 | P320 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
| S441 | T441 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S445 | I445 | Biomuta | DOID:3953 / adrenal gland cancer [ cosmic ] | |
| S445 | N445 | Biomuta | DOID:1793 / pancreatic cancer [ icgc ] |
DAG View