iPTMnet Report for Q8TE04 (PANK1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8TE04 / PANK1_HUMAN
Protein Name Pantothenate kinase 1
Gene Name Name: PANK1
Synonyms:PANK;
Organism Homo sapiens (Human)

PRO ID PR:Q8TE04
DAG View
PRO Name pantothenate kinase 1 (human)
Definition A pantothenate kinase 1 that is encoded in the genome of human.
Short Label hPANK1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8TE04 (PANK1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S152 Phosphorylation PhosphoSitePlus
S215 Phosphorylation PhosphoSitePlus   UniProt 19690332
S228 Phosphorylation PhosphoSitePlus
K271 Ubiquitination PhosphoSitePlus
Y276 Phosphorylation PhosphoSitePlus
T278 Phosphorylation PhosphoSitePlus
K285 Ubiquitination PhosphoSitePlus
K304 Ubiquitination PhosphoSitePlus
S314 Phosphorylation PhosphoSitePlus
T451 Phosphorylation PhosphoSitePlus
T455 Phosphorylation PhosphoSitePlus
K476 Ubiquitination PhosphoSitePlus
S508 Phosphorylation PhosphoSitePlus
K511 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T211 Phosphorylation PhosphoSitePlus
S218 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T278 N278 Biomuta DOID:3571 / liver cancer [ icgc ]
K285 E285 Biomuta DOID:1612 / breast cancer [ cosmic ]
S314 I314 Biomuta DOID:3571 / liver cancer [ tcga ]
T451 N451 Biomuta DOID:3571 / liver cancer [ icgc ]
S508 C508 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]