iPTMnet Report for Q8TDX6 (CSGALNACT1)
Protein Information
| UniProt AC / UniProt ID | Q8TDX6 / CGAT1_HUMAN |
| Protein Name | Chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
| Gene Name | Name: CSGALNACT1 Synonyms:CHGN,GALNACT1;ORFNames:UNQ656/PRO1287; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8TDX6 |
| PRO Name | chondroitin sulfate N-acetylgalactosaminyltransferase 1 (human) |
| Definition | A chondroitin sulfate N-acetylgalactosaminyltransferase 1 that is encoded in the genome of human. |
| Short Label | hCSGALNACT1 |
| Category | organism-gene |
Q8TDX6 (CSGALNACT1) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S50 | O-Glycosylation | score1 | GlyGen | 34846842 | ||
| T52 | O-Glycosylation | score1 | GlyGen | 34846842 | ||
| S101 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| T364 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T370 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T375 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T486 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y490 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S503 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T527 | Phosphorylation | score2 | IEDB PhosphoSitePlus | 35494241 | ||
| S528 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S50 | G50 | Biomuta | DOID:2531 / hematologic cancer [ cosmic, icgc ] | |
| T52 | A52 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| T52 | M52 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:3571 / liver cancer [ cosmic ] | |
| T370 | M370 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| T370 | A370 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
| Y490 | C490 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| S503 | P503 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |
DAG View