iPTMnet Report for Q8TDW7 (FAT3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8TDW7 / FAT3_HUMAN
Protein Name Protocadherin Fat 3 precursor
Gene Name Name: FAT3
Synonyms:CDHF15,KIAA1989;
Organism Homo sapiens (Human)

PRO ID PR:Q8TDW7
DAG View
PRO Name protocadherin Fat 3 (human)
Definition A protocadherin Fat 3 that is encoded in the genome of human.
Short Label hFAT3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8TDW7 (FAT3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S132 Phosphorylation PhosphoSitePlus
S216 Phosphorylation PhosphoSitePlus
Y227 Phosphorylation PhosphoSitePlus
Y381 Phosphorylation PhosphoSitePlus
S389 Phosphorylation PhosphoSitePlus
T565 Phosphorylation PhosphoSitePlus
N668 N-Glycosylation GlyGen 24190977
T686 Phosphorylation PhosphoSitePlus
S989 Phosphorylation PhosphoSitePlus
N1007 N-Glycosylation GlyGen 24190977
S1092 Phosphorylation PhosphoSitePlus
S1097 Phosphorylation PhosphoSitePlus
Y1495 Phosphorylation PhosphoSitePlus
S1499 Phosphorylation PhosphoSitePlus
S1503 Phosphorylation PhosphoSitePlus
Y1519 Phosphorylation PhosphoSitePlus
T1633 Phosphorylation PhosphoSitePlus
S1652 Phosphorylation PhosphoSitePlus
T1654 Phosphorylation PhosphoSitePlus
Y2154 Phosphorylation PhosphoSitePlus
T2157 Phosphorylation PhosphoSitePlus
T2440 Phosphorylation PhosphoSitePlus
S2446 Phosphorylation PhosphoSitePlus
S2870 Phosphorylation PhosphoSitePlus
T2872 Phosphorylation PhosphoSitePlus
Y3099 Phosphorylation PhosphoSitePlus
Y3273 Phosphorylation PhosphoSitePlus
T3867 Phosphorylation PhosphoSitePlus
T3877 Phosphorylation PhosphoSitePlus
Y3946 Phosphorylation PhosphoSitePlus
Y4044 Phosphorylation PhosphoSitePlus
Y4184 Phosphorylation PhosphoSitePlus
Y4222 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y1324 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S132 Y132 Biomuta DOID:363 / uterine cancer [ icgc ]
S389 F389 Biomuta [ cosmic ] DOID:4159 / skin cancer [ cosmic, icgc ]
T565 A565 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T686 A686 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S989 N989 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y1519 S1519 Biomuta DOID:4159 / skin cancer [ cosmic ]
T1633 A1633 Biomuta DOID:1324 / lung cancer [ cosmic ]
T1633 K1633 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T1633 M1633 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1540 / parathyroid carcinoma [ cosmic ]
Y2154 F2154 Biomuta DOID:1324 / lung cancer [ cosmic ]
T2157 A2157 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
T2440 M2440 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
S2446 N2446 Biomuta DOID:3571 / liver cancer [ cosmic ]
S2870 R2870 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T2872 M2872 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:10283 / prostate cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic, icgc ]
T3867 A3867 Biomuta DOID:2394 / ovarian cancer [ cosmic ]
Y4184 C4184 Biomuta DOID:363 / uterine cancer [ icgc ]