Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8TDQ0 / HAVR2_HUMAN
Protein Name Hepatitis A virus cellular receptor 2 precursor
Gene Name Name: HAVCR2
Synonyms:TIM3,TIMD3;
Organism Homo sapiens (Human)

PRO ID PR:Q8TDQ0
DAG View
PRO Name hepatitis A virus cellular receptor 2 (human)
Definition A hepatitis A virus cellular receptor 2 that is encoded in the genome of human.
Short Label hHAVCR2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8TDQ0 (HAVCR2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S105 Phosphorylation PhosphoSitePlus
Y108 Phosphorylation PhosphoSitePlus
K126 Acetylation PhosphoSitePlus
T145 O-Glycosylation UniProt 22171320
T153 Phosphorylation PhosphoSitePlus
T154 Phosphorylation PhosphoSitePlus
S238 Phosphorylation PhosphoSitePlus
S241 Phosphorylation PhosphoSitePlus
Y265 Phosphorylation Q08881 (ITK) PhosphoSitePlus   RLIMS-P   UniProt 17069754, 23967307
Y272 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S105 I105 Biomuta DOID:1324 / lung cancer [ tcga ]
K126 M126 Biomuta DOID:2596 / larynx cancer [ cosmic ]
S241 P241 Biomuta DOID:1324 / lung cancer [ tcga ]
S241 F241 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
Y265 H265 Biomuta DOID:3571 / liver cancer [ icgc ]