iPTMnet Report for Q8TDM6 (DLG5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8TDM6 / DLG5_HUMAN
Protein Name Disks large homolog 5
Gene Name Name: DLG5
Synonyms:KIAA0583,PDLG;
Organism Homo sapiens (Human)

PRO ID PR:Q8TDM6
DAG View
PRO Name disks large homolog 5 (human)
Definition A disks large homolog 5 that is encoded in the genome of human.
Short Label hDLG5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8TDM6 (DLG5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S37 Phosphorylation PhosphoSitePlus
K63 Ubiquitination PhosphoSitePlus
S132 Phosphorylation PhosphoSitePlus
S150 Phosphorylation PhosphoSitePlus
Y181 Phosphorylation PhosphoSitePlus
Y188 Phosphorylation PhosphoSitePlus
K192 Ubiquitination PhosphoSitePlus
S200 Phosphorylation PhosphoSitePlus
S204 Phosphorylation PhosphoSitePlus
T210 Phosphorylation PhosphoSitePlus
K214 Ubiquitination PhosphoSitePlus
Y226 Phosphorylation PhosphoSitePlus
S264 Phosphorylation PhosphoSitePlus   UniProt 23186163
K269 Ubiquitination PhosphoSitePlus
K277 Ubiquitination PhosphoSitePlus
K291 Ubiquitination PhosphoSitePlus
S295 Phosphorylation PhosphoSitePlus   UniProt 21406692, 20068231
S296 Phosphorylation PhosphoSitePlus
K327 Ubiquitination PhosphoSitePlus
K350 Ubiquitination PhosphoSitePlus
Y429 Phosphorylation PhosphoSitePlus
S430 Phosphorylation PhosphoSitePlus
Y432 Phosphorylation PhosphoSitePlus
K448 Ubiquitination PhosphoSitePlus
K459 Ubiquitination PhosphoSitePlus
S462 O-Glycosylation GlyGen 33214551, 30379171, 32574038, ...31492838, 35254053, 35132862, 35289036, 28657654
K510 Ubiquitination PhosphoSitePlus
S711 Phosphorylation PhosphoSitePlus
T718 Phosphorylation PhosphoSitePlus
S725 Phosphorylation PhosphoSitePlus
S730 Phosphorylation PhosphoSitePlus
S733 Phosphorylation PhosphoSitePlus
S773 Phosphorylation PhosphoSitePlus
S791 Phosphorylation PhosphoSitePlus
S803 Phosphorylation PhosphoSitePlus
S814 Phosphorylation PhosphoSitePlus
K816 Ubiquitination PhosphoSitePlus
S819 Phosphorylation PhosphoSitePlus
S841 Phosphorylation PhosphoSitePlus
S900 Phosphorylation PhosphoSitePlus   UniProt 23186163
S932 Phosphorylation PhosphoSitePlus
S938 Phosphorylation PhosphoSitePlus
S941 Phosphorylation PhosphoSitePlus
S943 Phosphorylation PhosphoSitePlus
T946 Phosphorylation PhosphoSitePlus
S962 Phosphorylation PhosphoSitePlus
Y964 Phosphorylation PhosphoSitePlus
K971 Ubiquitination PhosphoSitePlus
S972 Phosphorylation PhosphoSitePlus
T984 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983
Y990 Phosphorylation PhosphoSitePlus
S1000 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983
T1011 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S1021 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1064 Phosphorylation PhosphoSitePlus
S1075 Phosphorylation PhosphoSitePlus
S1076 Phosphorylation PhosphoSitePlus
Y1077 Phosphorylation PhosphoSitePlus
Y1078 Phosphorylation PhosphoSitePlus
S1086 Phosphorylation PhosphoSitePlus
K1091 Methylation PhosphoSitePlus
K1092 Methylation PhosphoSitePlus
S1093 Phosphorylation PhosphoSitePlus
S1115 Phosphorylation PhosphoSitePlus   RLIMS-P 30266825
S1146 Phosphorylation PhosphoSitePlus
S1156 Phosphorylation PhosphoSitePlus
S1171 Phosphorylation PhosphoSitePlus
S1181 O-Glycosylation GlyGen 34846842, 33214551, 30379171, ...32574038, 31492838, 35254053, 35132862, 35289036, 28657654
T1183 Phosphorylation PhosphoSitePlus   UniProt 23186163
T1186 O-Glycosylation GlyGen 33214551, 30379171, 32574038, ...31492838, 35254053, 35132862, 35289036, 28657654
T1187 O-Glycosylation GlyGen 33214551, 30379171, 32574038, ...31492838, 35254053, 35132862, 35289036, 28657654
S1189 O-Glycosylation GlyGen 32574038
Y1197 Phosphorylation PhosphoSitePlus
T1198 Phosphorylation PhosphoSitePlus
S1208 Phosphorylation PhosphoSitePlus
S1209 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1232 Phosphorylation phospho.ELM   PhosphoSitePlus 18220336
S1241 Phosphorylation PhosphoSitePlus
Y1243 Phosphorylation PhosphoSitePlus
S1244 Phosphorylation PhosphoSitePlus
T1249 Phosphorylation PhosphoSitePlus
S1252 Phosphorylation PhosphoSitePlus
S1254 Phosphorylation PhosphoSitePlus
S1263 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1264 Phosphorylation PhosphoSitePlus
S1265 Phosphorylation PhosphoSitePlus
T1279 Phosphorylation P28482 (MAPK1) neXtProt   PhosphoSitePlus 22028470
S1289 Phosphorylation PhosphoSitePlus
S1293 Phosphorylation PhosphoSitePlus
T1301 Phosphorylation PhosphoSitePlus
S1305 Phosphorylation PhosphoSitePlus
S1334 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y1344 Phosphorylation PhosphoSitePlus
S1357 Phosphorylation PhosphoSitePlus
S1363 Phosphorylation PhosphoSitePlus
S1478 Phosphorylation PhosphoSitePlus
T1479 Phosphorylation PhosphoSitePlus
T1559 O-Glycosylation GlyGen 33214551, 30379171, 32574038, ...31492838, 35254053, 35132862, 35289036, 28657654
K1587 Ubiquitination PhosphoSitePlus
K1589 Ubiquitination PhosphoSitePlus
S1666 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1668 Phosphorylation PhosphoSitePlus
K1678 Ubiquitination PhosphoSitePlus
K1773 Ubiquitination PhosphoSitePlus
K1784 Ubiquitination PhosphoSitePlus
S1795 Phosphorylation PhosphoSitePlus
K1867 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S132 Phosphorylation HPRD 19413330
S264 Phosphorylation HPRD 17322306, 18767875, 20068231
S295 Phosphorylation HPRD 19651622, 20068231
T984 Phosphorylation HPRD 17081983
S1000 Phosphorylation HPRD 17081983
S1004 Phosphorylation HPRD 18767875
T1011 Phosphorylation HPRD 18669648, 17924679
S1209 Phosphorylation HPRD 18767875, 19664995
S1263 Phosphorylation HPRD 17322306, 18767875, 19664994, ...19664995


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y181 H181 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S200 L200 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S296 F296 Biomuta DOID:4159 / skin cancer [ cosmic ]
S430 N430 Biomuta DOID:4362 / cervical cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
Y432 H432 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S711 F711 Biomuta [ cosmic ] DOID:4159 / skin cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S733 T733 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S841 F841 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S841 P841 Biomuta DOID:363 / uterine cancer [ icgc ]
S932 C932 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
T984 I984 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S1000 F1000 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S1021 Y1021 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1075 F1075 Biomuta DOID:4159 / skin cancer [ cosmic ]
K1091 N1091 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1093 F1093 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
S1146 F1146 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1156 L1156 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1264 L1264 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1265 N1265 Biomuta [ cosmic ]
S1293 P1293 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
T1301 S1301 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1334 F1334 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1357 P1357 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S1357 L1357 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1363 F1363 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K1589 T1589 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S1666 G1666 Biomuta DOID:1324 / lung cancer [ cosmic ]