iPTMnet Report for Q8TDI0 (CHD5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8TDI0 / CHD5_HUMAN
Protein Name Chromodomain-helicase-DNA-binding protein 5
Gene Name Name: CHD5
Synonyms:KIAA0444;
Organism Homo sapiens (Human)

PRO ID PR:Q8TDI0
DAG View
PRO Name chromodomain-helicase-DNA-binding protein 5 (human)
Definition A chromodomain-helicase-DNA-binding protein 5 that is encoded in the genome of human.
Short Label hCHD5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8TDI0 (CHD5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S86 Phosphorylation PhosphoSitePlus
K100 Acetylation PhosphoSitePlus
K102 Acetylation PhosphoSitePlus
K106 Acetylation PhosphoSitePlus
K107 Acetylation PhosphoSitePlus
K174 Acetylation PhosphoSitePlus
K175 Acetylation PhosphoSitePlus
T340 Phosphorylation PhosphoSitePlus
Y556 Phosphorylation PhosphoSitePlus
S558 Phosphorylation PhosphoSitePlus
S565 Phosphorylation PhosphoSitePlus
K588 Sumoylation PhosphoSitePlus
K588 Ubiquitination PhosphoSitePlus
Y610 Phosphorylation HPRD   PhosphoSitePlus 19664994
K858 Acetylation PhosphoSitePlus
K858 Ubiquitination PhosphoSitePlus
K918 Ubiquitination PhosphoSitePlus
K933 Ubiquitination PhosphoSitePlus
K938 Ubiquitination PhosphoSitePlus
K943 Ubiquitination PhosphoSitePlus
K958 Methylation PhosphoSitePlus
K961 Methylation PhosphoSitePlus
S1047 Phosphorylation PhosphoSitePlus
Y1062 Phosphorylation PhosphoSitePlus
T1169 Phosphorylation PhosphoSitePlus
K1194 Ubiquitination PhosphoSitePlus
T1217 Phosphorylation PhosphoSitePlus
K1237 Acetylation PhosphoSitePlus
K1310 Sumoylation PhosphoSitePlus
K1310 Ubiquitination PhosphoSitePlus
Y1319 Phosphorylation PhosphoSitePlus
K1322 Ubiquitination PhosphoSitePlus
R1325 Methylation PhosphoSitePlus
K1341 Ubiquitination PhosphoSitePlus
Q1390 Methylation UniProt 26797129
K1406 Sumoylation PhosphoSitePlus
K1406 Ubiquitination PhosphoSitePlus
K1430 Ubiquitination PhosphoSitePlus
R1465 Methylation PhosphoSitePlus
R1511 Methylation PhosphoSitePlus
S1631 Phosphorylation PhosphoSitePlus
S1654 Phosphorylation HPRD   PhosphoSitePlus 20068231
S1658 Phosphorylation HPRD   PhosphoSitePlus 20068231
T1670 Phosphorylation PhosphoSitePlus
R1755 Methylation PhosphoSitePlus
S1846 Phosphorylation PhosphoSitePlus
K1851 Ubiquitination PhosphoSitePlus
S1869 Phosphorylation PhosphoSitePlus
K1872 Ubiquitination PhosphoSitePlus
T1876 Phosphorylation PhosphoSitePlus
S1895 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K588 R588 Biomuta DOID:1324 / lung cancer [ cosmic ]
K588 N588 Biomuta DOID:1319 / brain cancer [ icgc ]
K918 N918 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K918 M918 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
K961 M961 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
K1237 Q1237 Biomuta DOID:3571 / liver cancer [ cosmic ]
K1322 M1322 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R1325 W1325 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
R1325 Q1325 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S1654 C1654 Biomuta DOID:1612 / breast cancer [ icgc ]
S1658 I1658 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S1846 F1846 Biomuta DOID:4159 / skin cancer [ cosmic ]
K1851 * Biomuta DOID:5041 / esophageal cancer [ cosmic ]