iPTMnet Report for Q8TDH9 (BLOC1S5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8TDH9 / BL1S5_HUMAN
Protein Name Biogenesis of lysosome-related organelles complex 1 subunit 5
Gene Name Name: BLOC1S5
Synonyms:MUTED;
Organism Homo sapiens (Human)

PRO ID PR:Q8TDH9
DAG View
PRO Name biogenesis of lysosome-related organelles complex 1 subunit 5 (human)
Definition A protein Muted that is encoded in the genome of human.
Short Label hBLOC1S5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8TDH9 (BLOC1S5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 19413330
S2 Phosphorylation PhosphoSitePlus
T8 Phosphorylation PhosphoSitePlus
S20 Phosphorylation PhosphoSitePlus
S25 Phosphorylation PhosphoSitePlus
T28 Phosphorylation PhosphoSitePlus
S31 Phosphorylation PhosphoSitePlus
K37 Ubiquitination PhosphoSitePlus
S44 Phosphorylation PhosphoSitePlus
K62 Ubiquitination PhosphoSitePlus
K80 Ubiquitination PhosphoSitePlus
C117 Methylation IEDB 31844290
S131 Phosphorylation PhosphoSitePlus
K139 Ubiquitination PhosphoSitePlus
K179 Acetylation PhosphoSitePlus
K183 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T8 S8 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S25 F25 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K62 E62 Biomuta DOID:1612 / breast cancer [ cosmic ]