Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8TD57 / DYH3_HUMAN
Protein Name Dynein axonemal heavy chain 3
Gene Name Name: DNAH3
Synonyms:DNAHC3B;
Organism Homo sapiens (Human)

PRO ID PR:Q8TD57
DAG View
PRO Name dynein axonemal heavy chain 3 (human)
Definition A dynein axonemal heavy chain 3 that is encoded in the genome of human.
Short Label hDNAH3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8TD57 (DNAH3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K98 Acetylation PhosphoSitePlus
T142 Phosphorylation PhosphoSitePlus
K160 Acetylation PhosphoSitePlus
R167 Methylation PhosphoSitePlus
R174 Methylation PhosphoSitePlus
S313 Phosphorylation PhosphoSitePlus
Y571 Phosphorylation PhosphoSitePlus
T577 Phosphorylation PhosphoSitePlus
T620 Phosphorylation PhosphoSitePlus
K630 Acetylation PhosphoSitePlus
S713 Phosphorylation PhosphoSitePlus
T719 Phosphorylation PhosphoSitePlus
S724 Phosphorylation PhosphoSitePlus
K731 Acetylation PhosphoSitePlus
K739 Acetylation PhosphoSitePlus
Y856 Phosphorylation PhosphoSitePlus
S1314 Phosphorylation PhosphoSitePlus
K1444 Methylation PhosphoSitePlus
K1682 Acetylation PhosphoSitePlus
K1692 Acetylation PhosphoSitePlus
Y1743 Phosphorylation PhosphoSitePlus
S2118 Phosphorylation PhosphoSitePlus
S2636 Phosphorylation PhosphoSitePlus
Y2639 Phosphorylation PhosphoSitePlus
Y2640 Phosphorylation PhosphoSitePlus
K2796 Methylation PhosphoSitePlus
Y2826 Phosphorylation PhosphoSitePlus
Y2846 Phosphorylation PhosphoSitePlus
K2921 Ubiquitination PhosphoSitePlus
S2972 Phosphorylation PhosphoSitePlus
T2982 Phosphorylation PhosphoSitePlus
K3100 Acetylation PhosphoSitePlus
S3228 Phosphorylation PhosphoSitePlus
Y3696 Phosphorylation PhosphoSitePlus
Y3717 Phosphorylation PhosphoSitePlus
S3835 O-Glycosylation GlyGen 29351928
Y3864 Phosphorylation PhosphoSitePlus
Y3868 Phosphorylation PhosphoSitePlus
S3893 Phosphorylation PhosphoSitePlus
Y3932 Phosphorylation PhosphoSitePlus
Y3941 Phosphorylation PhosphoSitePlus
T4031 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K98 T98 Biomuta DOID:1909 / melanoma [ cosmic ]
T620 M620 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
Y856 * Biomuta DOID:3571 / liver cancer [ icgc ]
K1692 E1692 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
Y1743 H1743 Biomuta DOID:0070003 / blastoma [ cosmic ]
S2118 C2118 Biomuta DOID:2394 / ovarian cancer [ tcga ]
K3100 N3100 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y3717 * Biomuta DOID:3571 / liver cancer [ icgc ]
S3835 C3835 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
Y3864 * Biomuta DOID:3571 / liver cancer [ icgc ]
Y3941 C3941 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
T4031 M4031 Biomuta DOID:1909 / melanoma [ icgc, tcga ] DOID:11934 / head and neck cancer [ tcga ]