iPTMnet Report for Q8TD43 (TRPM4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8TD43 / TRPM4_HUMAN
Protein Name Transient receptor potential cation channel subfamily M member 4
Gene Name Name: TRPM4
Synonyms:LTRPC4;
Organism Homo sapiens (Human)

PRO ID PR:Q8TD43
DAG View
PRO Name transient receptor potential cation channel subfamily M member 4 (human)
Definition A transient receptor potential cation channel subfamily M member 4 that is encoded in the genome of human.
Short Label hTRPM4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8TD43 (TRPM4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T97 Phosphorylation PhosphoSitePlus
S104 Phosphorylation PhosphoSitePlus
S255 Phosphorylation PhosphoSitePlus
S411 Phosphorylation PhosphoSitePlus
S483 Phosphorylation PhosphoSitePlus
T486 Phosphorylation PhosphoSitePlus
K487 Ubiquitination PhosphoSitePlus
K492 Ubiquitination PhosphoSitePlus
S839 Phosphorylation PhosphoSitePlus   RLIMS-P 25231975
S839 Phosphorylation P49674 (CSNK1E) PhosphoSitePlus 25231975
N992 N-Glycosylation GlyGen   UniProt 29217581
K1059 Ubiquitination PhosphoSitePlus
S1102 Phosphorylation PhosphoSitePlus
S1103 Phosphorylation PhosphoSitePlus
Y1112 Phosphorylation PhosphoSitePlus
K1115 Ubiquitination PhosphoSitePlus
K1129 Ubiquitination PhosphoSitePlus
S1145 Phosphorylation PhosphoSitePlus   Signor   UniProt 15590641
S1145 Phosphorylation P17252 (PRKCA) PhosphoSitePlus   Signor 15590641
S1152 Phosphorylation PhosphoSitePlus   Signor   UniProt 15590641
S1152 Phosphorylation P17252 (PRKCA) PhosphoSitePlus   Signor 15590641
K1160 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S104 Phosphorylation HPRD 19413330


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T97 M97 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S483 G483 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K492 E492 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S1145 F1145 Biomuta DOID:4159 / skin cancer [ cosmic ]