iPTMnet Report for Q8TCU4 (ALMS1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8TCU4 / ALMS1_HUMAN
Protein Name Centrosome-associated protein ALMS1
Gene Name Name: ALMS1
Synonyms:KIAA0328;
Organism Homo sapiens (Human)

PRO ID PR:Q8TCU4
DAG View
PRO Name centrosome-associated protein ALMS1 (human)
Definition A centrosome-associated protein ALMS1 that is encoded in the genome of human.
Short Label hALMS1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8TCU4 (ALMS1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S92 Phosphorylation PhosphoSitePlus
T152 Phosphorylation PhosphoSitePlus
S189 Phosphorylation PhosphoSitePlus
Y339 Phosphorylation PhosphoSitePlus
S344 Phosphorylation PhosphoSitePlus
Y345 Phosphorylation PhosphoSitePlus
K349 Ubiquitination PhosphoSitePlus
S393 Phosphorylation PhosphoSitePlus
Y394 Phosphorylation PhosphoSitePlus
Y397 Phosphorylation PhosphoSitePlus
Y453 Phosphorylation PhosphoSitePlus
S464 Phosphorylation PhosphoSitePlus   UniProt 23186163
T467 Phosphorylation PhosphoSitePlus
K470 Acetylation PhosphoSitePlus
K473 Acetylation PhosphoSitePlus
K476 Acetylation PhosphoSitePlus
S511 Phosphorylation PhosphoSitePlus
T555 Phosphorylation IEDB 35494241
T567 Phosphorylation PhosphoSitePlus
S576 Phosphorylation PhosphoSitePlus
Y632 Phosphorylation PhosphoSitePlus
S699 Phosphorylation PhosphoSitePlus
T706 Phosphorylation PhosphoSitePlus
S713 Phosphorylation PhosphoSitePlus
T714 Phosphorylation PhosphoSitePlus
K721 Ubiquitination PhosphoSitePlus
T746 Phosphorylation PhosphoSitePlus
T754 Phosphorylation PhosphoSitePlus
S763 Phosphorylation PhosphoSitePlus
Y764 Phosphorylation PhosphoSitePlus
S765 Phosphorylation PhosphoSitePlus
K769 Ubiquitination PhosphoSitePlus
K800 Ubiquitination PhosphoSitePlus
Y811 Phosphorylation PhosphoSitePlus
S841 Phosphorylation PhosphoSitePlus
K866 Ubiquitination PhosphoSitePlus
Y871 Phosphorylation PhosphoSitePlus
T881 Phosphorylation PhosphoSitePlus
K897 Acetylation PhosphoSitePlus
K897 Ubiquitination PhosphoSitePlus
K913 Ubiquitination PhosphoSitePlus
S951 O-Glycosylation GlyGen 33214551, 34019948, 30379171, ...29351928, 30059200, 35254053, 35132862, 31492838, 30620550, 31373491
K960 Ubiquitination PhosphoSitePlus
S978 Phosphorylation PhosphoSitePlus
K980 Ubiquitination PhosphoSitePlus
S982 Phosphorylation PhosphoSitePlus
T988 Phosphorylation PhosphoSitePlus
T995 O-Glycosylation GlyGen 31373491
T995 Phosphorylation IEDB 32387766
T997 Phosphorylation PhosphoSitePlus
S1002 O-Glycosylation GlyGen 31373491
K1008 Ubiquitination PhosphoSitePlus
K1028 Ubiquitination PhosphoSitePlus
S1030 Phosphorylation PhosphoSitePlus
Y1050 Phosphorylation PhosphoSitePlus
K1055 Ubiquitination PhosphoSitePlus
Y1060 Phosphorylation PhosphoSitePlus
S1067 Phosphorylation PhosphoSitePlus
S1073 Phosphorylation PhosphoSitePlus
Y1107 Phosphorylation PhosphoSitePlus
T1136 O-Glycosylation GlyGen 33214551, 34019948, 30379171, ...29351928, 30059200, 35254053, 35132862, 31492838, 30620550, 31373491
T1142 O-Glycosylation GlyGen 33214551, 34019948, 30379171, ...29351928, 30059200, 35254053, 35132862, 31492838, 30620550, 31373491
S1143 O-Glycosylation GlyGen 33214551, 34019948, 30379171, ...29351928, 30059200, 35254053, 35132862, 31492838, 30620550, 31373491
S1189 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y1192 Phosphorylation PhosphoSitePlus
S1193 Phosphorylation PhosphoSitePlus
S1219 Phosphorylation PhosphoSitePlus
S1236 O-Glycosylation GlyGen 33214551, 34019948, 30379171, ...29351928, 30059200, 35254053, 35132862, 31492838, 30620550, 31373491
T1242 O-Glycosylation GlyGen 33214551, 34019948, 30379171, ...29351928, 30059200, 35254053, 35132862, 31492838, 30620550, 31373491
Y1249 Phosphorylation PhosphoSitePlus
S1266 O-Glycosylation GlyGen 33214551, 34019948, 30379171, ...29351928, 30059200, 35254053, 35132862, 31492838, 30620550, 31373491
S1269 O-Glycosylation GlyGen 30620550
S1269 Phosphorylation PhosphoSitePlus
T1275 O-Glycosylation GlyGen 33214551, 34019948, 30379171, ...29351928, 30059200, 35254053, 35132862, 31492838, 30620550, 31373491
T1275 Phosphorylation PhosphoSitePlus
T1276 O-Glycosylation GlyGen 33214551, 34019948, 30379171, ...29351928, 30059200, 35254053, 35132862, 31492838, 30620550, 31373491
T1282 O-Glycosylation GlyGen 33214551, 34019948, 30379171, ...29351928, 30059200, 35254053, 35132862, 31492838, 30620550, 31373491
S1283 O-Glycosylation GlyGen 33214551, 34019948, 30379171, ...29351928, 30059200, 35254053, 35132862, 31492838, 30620550, 31373491
S1285 Phosphorylation PhosphoSitePlus
Y1297 Phosphorylation PhosphoSitePlus
S1300 O-Glycosylation GlyGen 33214551, 34019948, 30379171, ...29351928, 30059200, 35254053, 35132862, 31492838, 30620550, 31373491
S1300 Phosphorylation PhosphoSitePlus
S1303 O-Glycosylation GlyGen 33214551, 34019948, 30379171, ...29351928, 30059200, 35254053, 35132862, 31492838, 30620550, 31373491
S1335 Phosphorylation IEDB 32387766
Y1344 Phosphorylation PhosphoSitePlus
T1373 O-Glycosylation GlyGen 33214551, 34019948, 30379171, ...29351928, 30059200, 35254053, 35132862, 31492838, 30620550, 31373491
Y1392 Phosphorylation PhosphoSitePlus
S1503 O-Glycosylation GlyGen 32938750
T1512 O-Glycosylation GlyGen 33214551, 34019948, 30379171, ...29351928, 32938750, 30059200, 30620550, 35132862, 31492838, 35254053, 31373491
T1513 O-Glycosylation GlyGen 32938750
T1519 Phosphorylation PhosphoSitePlus
S1530 Phosphorylation PhosphoSitePlus
S1532 Phosphorylation PhosphoSitePlus
T1560 O-Glycosylation GlyGen 33214551, 34019948, 30379171, ...29351928, 30059200, 35254053, 35132862, 31492838, 30620550, 31373491
K1623 Acetylation PhosphoSitePlus
S1635 Phosphorylation PhosphoSitePlus
S1645 O-Glycosylation GlyGen 33214551, 34019948, 30379171, ...29351928, 30059200, 35254053, 35132862, 31492838, 30620550, 31373491
S1662 O-Glycosylation GlyGen 33214551, 34019948, 30379171, ...29351928, 30059200, 35254053, 35132862, 31492838, 30620550, 31373491
T1663 Phosphorylation PhosphoSitePlus
K1670 Acetylation PhosphoSitePlus
S1706 O-Glycosylation GlyGen 31373491
S1708 O-Glycosylation GlyGen 33214551, 34019948, 30379171, ...29351928, 30059200, 35254053, 35132862, 31492838, 30620550, 31373491
Y1712 Phosphorylation PhosphoSitePlus
S1713 O-Glycosylation GlyGen 31373491
K1717 Ubiquitination PhosphoSitePlus
S1786 O-Glycosylation GlyGen 33214551, 34019948, 30379171, ...29351928, 30059200, 35254053, 35132862, 31492838, 30620550, 31373491
T1796 O-Glycosylation GlyGen 33214551, 34019948, 30379171, ...29351928, 30059200, 35254053, 35132862, 31492838, 30620550, 31373491
T1802 O-Glycosylation GlyGen 33214551, 34019948, 30379171, ...29351928, 30059200, 35254053, 35132862, 31492838, 30620550, 31373491
S1803 O-Glycosylation GlyGen 30059200, 29351928
S1805 O-Glycosylation GlyGen 33214551, 34019948, 30379171, ...29351928, 30059200, 35254053, 35132862, 31492838, 30620550, 31373491
K1811 Ubiquitination PhosphoSitePlus
K1829 Ubiquitination PhosphoSitePlus
K1840 Ubiquitination PhosphoSitePlus
S1857 Phosphorylation PhosphoSitePlus
K1874 Ubiquitination PhosphoSitePlus
K1930 Ubiquitination PhosphoSitePlus
Y1940 Phosphorylation PhosphoSitePlus
Y1941 Phosphorylation PhosphoSitePlus
S1942 Phosphorylation PhosphoSitePlus
K1946 Ubiquitination PhosphoSitePlus
S1968 Phosphorylation PhosphoSitePlus
K2008 Ubiquitination PhosphoSitePlus
K2024 Ubiquitination PhosphoSitePlus
K2026 Ubiquitination PhosphoSitePlus
K2053 Ubiquitination PhosphoSitePlus
K2087 Ubiquitination PhosphoSitePlus
K2100 Ubiquitination PhosphoSitePlus
S2101 Phosphorylation PhosphoSitePlus
K2131 Ubiquitination PhosphoSitePlus
S2143 Phosphorylation PhosphoSitePlus   UniProt 23186163
K2147 Ubiquitination PhosphoSitePlus
K2154 Ubiquitination PhosphoSitePlus
K2167 Ubiquitination PhosphoSitePlus
K2196 Ubiquitination PhosphoSitePlus
K2235 Ubiquitination PhosphoSitePlus
S2246 Phosphorylation PhosphoSitePlus
S2255 Phosphorylation PhosphoSitePlus
K2257 Ubiquitination PhosphoSitePlus
K2275 Ubiquitination PhosphoSitePlus
K2298 Ubiquitination PhosphoSitePlus
K2299 Ubiquitination PhosphoSitePlus
K2304 Ubiquitination PhosphoSitePlus
S2308 Phosphorylation PhosphoSitePlus
K2334 Ubiquitination PhosphoSitePlus
K2343 Ubiquitination PhosphoSitePlus
T2358 Phosphorylation PhosphoSitePlus
K2369 Ubiquitination PhosphoSitePlus
K2385 Ubiquitination PhosphoSitePlus
K2402 Ubiquitination PhosphoSitePlus
T2409 Phosphorylation PhosphoSitePlus
S2466 Phosphorylation PhosphoSitePlus   UniProt 23186163, 24275569
K2484 Ubiquitination PhosphoSitePlus
S2491 Phosphorylation PhosphoSitePlus
S2492 Phosphorylation PhosphoSitePlus
K2497 Ubiquitination PhosphoSitePlus
K2518 Ubiquitination PhosphoSitePlus
K2539 Ubiquitination PhosphoSitePlus
K2544 Ubiquitination PhosphoSitePlus
T2553 O-Glycosylation GlyGen 33214551, 34019948, 30379171, ...29351928, 30059200, 35254053, 35132862, 31492838, 30620550, 31373491
K2558 Ubiquitination PhosphoSitePlus
K2569 Ubiquitination PhosphoSitePlus
C2586 Methylation IEDB 31844290
T2613 O-Glycosylation GlyGen 33214551, 34019948, 30379171, ...29351928, 30059200, 35254053, 35132862, 31492838, 30620550, 31373491
R2614 Methylation PhosphoSitePlus
K2625 Ubiquitination PhosphoSitePlus
S2632 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231
S2645 Phosphorylation PhosphoSitePlus
K2649 Ubiquitination PhosphoSitePlus
S2652 Phosphorylation PhosphoSitePlus
K2663 Ubiquitination PhosphoSitePlus
K2666 Ubiquitination PhosphoSitePlus
R2669 Methylation PhosphoSitePlus
K2675 Ubiquitination PhosphoSitePlus
S2704 Phosphorylation PhosphoSitePlus
T2713 Phosphorylation PhosphoSitePlus
K2724 Ubiquitination PhosphoSitePlus
S2752 Phosphorylation PhosphoSitePlus
T2755 Phosphorylation PhosphoSitePlus
T2768 Phosphorylation PhosphoSitePlus
S2769 Phosphorylation PhosphoSitePlus
K2775 Ubiquitination PhosphoSitePlus
S2780 Phosphorylation PhosphoSitePlus
K2783 Ubiquitination PhosphoSitePlus
S2795 Phosphorylation PhosphoSitePlus
K2797 Ubiquitination PhosphoSitePlus
S2805 Phosphorylation PhosphoSitePlus   UniProt 23186163
K2810 Ubiquitination PhosphoSitePlus
T2818 Phosphorylation PhosphoSitePlus
K2834 Ubiquitination PhosphoSitePlus
K2868 Ubiquitination PhosphoSitePlus
T2873 Phosphorylation PhosphoSitePlus
K2892 Ubiquitination PhosphoSitePlus
K2902 Ubiquitination PhosphoSitePlus
K2934 Ubiquitination PhosphoSitePlus
S2947 Phosphorylation PhosphoSitePlus
S2962 Phosphorylation PhosphoSitePlus
C3028 Methylation IEDB 31844290
S3035 Phosphorylation PhosphoSitePlus
T3036 Phosphorylation PhosphoSitePlus
S3045 Phosphorylation PhosphoSitePlus
K3058 Ubiquitination PhosphoSitePlus
T3063 Phosphorylation PhosphoSitePlus
S3070 Phosphorylation PhosphoSitePlus
K3076 Ubiquitination PhosphoSitePlus
K3100 Ubiquitination PhosphoSitePlus
K3105 Ubiquitination PhosphoSitePlus
S3113 Phosphorylation PhosphoSitePlus
K3120 Ubiquitination PhosphoSitePlus
S3121 Phosphorylation PhosphoSitePlus
S3122 Phosphorylation PhosphoSitePlus
S3147 Phosphorylation PhosphoSitePlus
S3150 Phosphorylation PhosphoSitePlus
T3174 Phosphorylation PhosphoSitePlus
K3195 Ubiquitination PhosphoSitePlus
S3208 Phosphorylation PhosphoSitePlus
K3236 Ubiquitination PhosphoSitePlus
S3256 Phosphorylation PhosphoSitePlus
K3269 Ubiquitination PhosphoSitePlus
K3275 Ubiquitination PhosphoSitePlus
Y3277 Phosphorylation PhosphoSitePlus
Y3278 Phosphorylation PhosphoSitePlus
Y3337 Phosphorylation PhosphoSitePlus
K3430 Ubiquitination PhosphoSitePlus
K3435 Ubiquitination PhosphoSitePlus
K3442 Ubiquitination PhosphoSitePlus
K3503 Ubiquitination PhosphoSitePlus
S3510 Phosphorylation PhosphoSitePlus
K3512 Ubiquitination PhosphoSitePlus
K3521 Acetylation PhosphoSitePlus
K3521 Ubiquitination PhosphoSitePlus
T3538 Phosphorylation PhosphoSitePlus
S3549 Phosphorylation PhosphoSitePlus
K3564 Ubiquitination PhosphoSitePlus
K3572 Ubiquitination PhosphoSitePlus
K3585 Ubiquitination PhosphoSitePlus
K3604 Ubiquitination PhosphoSitePlus
K3621 Ubiquitination PhosphoSitePlus
K3661 Ubiquitination PhosphoSitePlus
S3681 Phosphorylation PhosphoSitePlus
K3710 Sumoylation PhosphoSitePlus
K3715 Ubiquitination PhosphoSitePlus
S3780 Phosphorylation PhosphoSitePlus
S3781 Phosphorylation PhosphoSitePlus
C3800 Methylation IEDB 31844290
S3802 Phosphorylation PhosphoSitePlus
S3811 Phosphorylation PhosphoSitePlus
K3885 Ubiquitination PhosphoSitePlus
K3953 Ubiquitination PhosphoSitePlus
S3972 Phosphorylation PhosphoSitePlus
T3980 Phosphorylation PhosphoSitePlus
K4067 Ubiquitination PhosphoSitePlus
K4098 Ubiquitination PhosphoSitePlus
K4120 Acetylation PhosphoSitePlus
Y4123 Phosphorylation PhosphoSitePlus
K4132 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T152 R152 Biomuta DOID:1324 / lung cancer [ cosmic ]
S189 Y189 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y394 H394 Biomuta DOID:363 / uterine cancer [ cosmic ]
K476 N476 Biomuta DOID:1319 / brain cancer [ cosmic ]
T567 I567 Biomuta DOID:363 / uterine cancer [ cosmic ]
S576 * Biomuta DOID:4159 / skin cancer [ cosmic ]
S576 A576 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
T714 S714 Biomuta DOID:2394 / ovarian cancer [ cosmic ]
S763 A763 Biomuta DOID:363 / uterine cancer [ cosmic ]
S763 F763 Biomuta DOID:4362 / cervical cancer [ cosmic ]
S765 L765 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
K800 E800 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S978 F978 Biomuta DOID:1612 / breast cancer [ cosmic ]
S1030 T1030 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y1050 * Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
T1142 I1142 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
T1242 R1242 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1269 F1269 Biomuta DOID:1612 / breast cancer [ cosmic ]
T1282 S1282 Biomuta DOID:1324 / lung cancer [ cosmic ]
S1303 G1303 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y1344 H1344 Biomuta DOID:4159 / skin cancer [ cosmic ]
T1519 P1519 Biomuta DOID:2394 / ovarian cancer [ cosmic ]
T1663 I1663 Biomuta DOID:1324 / lung cancer [ cosmic ]
T1663 S1663 Biomuta DOID:1324 / lung cancer [ cosmic ]
S1706 L1706 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1706 P1706 Biomuta DOID:1612 / breast cancer [ cosmic ]
K1930 N1930 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S1942 P1942 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K2024 R2024 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
K2026 R2026 Biomuta DOID:3571 / liver cancer [ cosmic ]
K2154 R2154 Biomuta DOID:3571 / liver cancer [ cosmic ]
K2167 N2167 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K2235 T2235 Biomuta DOID:363 / uterine cancer [ cosmic ]
K2298 N2298 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S2308 F2308 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ]
T2409 S2409 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
K2484 E2484 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S2491 Y2491 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
K2518 Q2518 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K2569 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S2645 F2645 Biomuta DOID:1324 / lung cancer [ cosmic ]
K2663 R2663 Biomuta DOID:263 / kidney cancer [ cosmic ]
K2666 I2666 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
R2669 Q2669 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R2669 * Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
S2769 C2769 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S2780 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S2780 L2780 Biomuta DOID:4159 / skin cancer [ cosmic ]
T2818 A2818 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
K2868 N2868 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
C3028 G3028 Biomuta DOID:1319 / brain cancer [ cosmic ]
K3236 N3236 Biomuta DOID:1324 / lung cancer [ cosmic ]
K3269 * Biomuta DOID:3571 / liver cancer [ cosmic ]
K3521 R3521 Biomuta DOID:1324 / lung cancer [ cosmic ]
K3604 T3604 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S3811 N3811 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K3885 N3885 Biomuta DOID:1324 / lung cancer [ cosmic ]
K3885 R3885 Biomuta DOID:1324 / lung cancer [ cosmic ]
K4067 M4067 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
K4120 T4120 Biomuta DOID:363 / uterine cancer [ cosmic ]