iPTMnet Report Q8TCT0 CERK

Protein Information

Cytoscape View

UniProt AC / UniProt ID	Q8TCT0 / CERK1_HUMAN
Protein Name	Ceramide kinase
Gene Name	Name: CERK Synonyms:KIAA1646;
Organism	Homo sapiens (Human)

PRO ID	PR:Q8TCT0 DAG View
PRO Name	ceramide kinase (human)
Definition	A ceramide kinase that is encoded in the genome of human.
Short Label	hCERK
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

Q8TCT0 (CERK) as Substrate

Q8TCT0

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S340	Phosphorylation		score3	PhosphoSitePlus RLIMS-P UniProt	19899769
	S357	Phosphorylation		score1	PhosphoSitePlus
	S408	Phosphorylation		score3	PhosphoSitePlus RLIMS-P UniProt	19899769
	S427	Phosphorylation		score1	PhosphoSitePlus
	K457	Ubiquitination		score1	PhosphoSitePlus
	K473	Ubiquitination		score1	PhosphoSitePlus
	K477	Ubiquitination		score1	PhosphoSitePlus
	K478	Ubiquitination		score1	PhosphoSitePlus

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
K477	E477	Biomuta		DOID:363 / uterine cancer [ tcga ]