iPTMnet Report for Q8TCT0 (CERK)
Protein Information
| UniProt AC / UniProt ID | Q8TCT0 / CERK1_HUMAN |
| Protein Name | Ceramide kinase |
| Gene Name | Name: CERK Synonyms:KIAA1646; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8TCT0 |
| PRO Name | ceramide kinase (human) |
| Definition | A ceramide kinase that is encoded in the genome of human. |
| Short Label | hCERK |
| Category | organism-gene |
DAG ViewQ8TCT0 (CERK) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| C324 | Methylation | score1 | IEDB | 31844290 | ||
| S340 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P UniProt | 19899769 | ||
| S357 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S408 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P UniProt | 19899769 | ||
| S427 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K457 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K473 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K477 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K478 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| C324 | Y324 | Biomuta | DOID:4362 / cervical cancer [ icgc ] | |
| S357 | R357 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
| K473 | R473 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
| K477 | E477 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |
