iPTMnet Report for Q8TCJ2 (STT3B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8TCJ2 / STT3B_HUMAN
Protein Name Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B
Gene Name Name: STT3B
Synonyms:SIMP;
Organism Homo sapiens (Human)

PRO ID PR:Q8TCJ2
DAG View
PRO Name dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B (human)
Definition A dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B that is encoded in the genome of human.
Short Label hSTT3B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8TCJ2 (STT3B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330
S9 Phosphorylation PhosphoSitePlus
K10 Ubiquitination PhosphoSitePlus
K12 Ubiquitination PhosphoSitePlus
S13 Phosphorylation HPRD   PhosphoSitePlus 18691976, 20068231
S14 Phosphorylation PhosphoSitePlus
S17 Phosphorylation HPRD   PhosphoSitePlus 20068231
S18 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19651622, 18669648, 20068231
S21 Phosphorylation HPRD   PhosphoSitePlus 20068231
S29 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 18767875, ...18452278, 18669648, 19690332
K52 Ubiquitination PhosphoSitePlus
T345 Phosphorylation PhosphoSitePlus
S498 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 21406692, 23186163, ...17081983, 19691289, 18452278, 19651622, 18669648, 19415658, 20068231
S499 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 18452278, ...19651622, 18669648, 19415658
K504 Ubiquitination PhosphoSitePlus
Y511 Phosphorylation PhosphoSitePlus
K513 Ubiquitination PhosphoSitePlus
K519 Ubiquitination PhosphoSitePlus
K526 Ubiquitination PhosphoSitePlus
T527 Phosphorylation PhosphoSitePlus
C554 Methylation IEDB 31844290
N616 N-Glycosylation GlyGen 29741879, 24190977
T618 O-Glycosylation GlyGen 34846842
T619 O-Glycosylation GlyGen 34846842, 32574038, 34725712, ...30059200, 35254053, 34019948, 35083852
N623 N-Glycosylation GlyGen   UniProt 29741879, 19159218, 24190977
N624 N-Glycosylation GlyGen 24190977
T625 O-Glycosylation GlyGen 34846842, 32574038, 34725712, ...30059200, 35254053, 34019948, 35083852
N627 N-Glycosylation GlyGen   UniProt 29741879, 19159218, 24190977
N628 N-Glycosylation GlyGen 24190977
S629 O-Glycosylation GlyGen 34846842, 32574038, 34725712, ...30059200, 35254053, 34019948, 35083852
S639 O-Glycosylation GlyGen 32574038
S639 Phosphorylation PhosphoSitePlus
S640 Phosphorylation PhosphoSitePlus
N641 N-Glycosylation GlyGen 23090970, 29741879, 24190977
T643 Phosphorylation PhosphoSitePlus
Y646 Phosphorylation PhosphoSitePlus
K647 Ubiquitination PhosphoSitePlus
K688 Ubiquitination PhosphoSitePlus
S693 Phosphorylation PhosphoSitePlus
Y695 Phosphorylation PhosphoSitePlus
K706 Ubiquitination PhosphoSitePlus
C715 Methylation IEDB 31844290
Y718 Phosphorylation PhosphoSitePlus
K719 Ubiquitination PhosphoSitePlus
S721 Phosphorylation PhosphoSitePlus
K749 Ubiquitination PhosphoSitePlus
K752 Ubiquitination PhosphoSitePlus
K754 Acetylation PhosphoSitePlus
K754 Ubiquitination PhosphoSitePlus
K784 Ubiquitination PhosphoSitePlus
K793 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
N616 N-Glycosylation PRO 29741879
N623 N-Glycosylation PRO 29741879
N627 N-Glycosylation PRO 29741879
N641 N-Glycosylation PRO 29741879


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S18 C18 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
T527 N527 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S639 F639 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
Y695 S695 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S721 L721 Biomuta DOID:1324 / lung cancer [ cosmic ]
K749 T749 Biomuta DOID:363 / uterine cancer [ icgc ]
K793 N793 Biomuta DOID:9256 / colorectal cancer [ cosmic ]