iPTMnet Report for Q8TCJ0 (FBXO25)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8TCJ0 / FBX25_HUMAN
Protein Name F-box only protein 25
Gene Name Name: FBXO25
Synonyms:FBX25;
Organism Homo sapiens (Human)

PRO ID PR:Q8TCJ0
DAG View
PRO Name F-box only protein 25 (human)
Definition An F-box only protein 25 that is encoded in the genome of human.
Short Label hFBXO25
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8TCJ0 (FBXO25) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K17 Ubiquitination PhosphoSitePlus
K31 Ubiquitination PhosphoSitePlus
K65 Ubiquitination PhosphoSitePlus
K69 Ubiquitination PhosphoSitePlus
K85 Ubiquitination PhosphoSitePlus
Y124 Phosphorylation PhosphoSitePlus
K134 Ubiquitination PhosphoSitePlus
K146 Ubiquitination PhosphoSitePlus
Y148 Phosphorylation PhosphoSitePlus
K154 Ubiquitination PhosphoSitePlus
K158 Ubiquitination PhosphoSitePlus
S178 Phosphorylation PhosphoSitePlus
K271 Ubiquitination PhosphoSitePlus
K280 Ubiquitination PhosphoSitePlus
K310 Ubiquitination PhosphoSitePlus
S351 Phosphorylation PhosphoSitePlus
T354 Phosphorylation PhosphoSitePlus
K366 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T20 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y124 S124 Biomuta DOID:1612 / breast cancer [ cosmic ]
K146 N146 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K146 Q146 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S178 Y178 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S178 F178 Biomuta DOID:4159 / skin cancer [ cosmic ]
T354 A354 Biomuta DOID:3571 / liver cancer [ cosmic ]
T354 M354 Biomuta DOID:10534 / stomach cancer [ cosmic ]