iPTMnet Report for Q8TCG2 (PI4K2B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8TCG2 / P4K2B_HUMAN
Protein Name Phosphatidylinositol 4-kinase type 2-beta
Gene Name Name: PI4K2B
Organism Homo sapiens (Human)

PRO ID PR:Q8TCG2
DAG View
PRO Name phosphatidylinositol 4-kinase type 2-beta (human)
Definition A phosphatidylinositol 4-kinase type 2-beta that is encoded in the genome of human.
Short Label hPI4K2B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8TCG2 (PI4K2B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S12 Phosphorylation PhosphoSitePlus   UniProt 19369195
S17 Phosphorylation PhosphoSitePlus   UniProt 19369195
S45 Phosphorylation PhosphoSitePlus   UniProt 24275569
S133 Phosphorylation PhosphoSitePlus
Y134 Phosphorylation PhosphoSitePlus
K137 Ubiquitination PhosphoSitePlus
K140 Ubiquitination PhosphoSitePlus
K142 Ubiquitination PhosphoSitePlus
K148 Ubiquitination PhosphoSitePlus
K150 Ubiquitination PhosphoSitePlus
Y155 Phosphorylation PhosphoSitePlus
K161 Ubiquitination PhosphoSitePlus
K164 Ubiquitination PhosphoSitePlus
K168 Ubiquitination PhosphoSitePlus
K236 Ubiquitination PhosphoSitePlus
S255 Phosphorylation PhosphoSitePlus
K272 Ubiquitination PhosphoSitePlus
K284 Ubiquitination PhosphoSitePlus
Y298 Phosphorylation PhosphoSitePlus
K329 Ubiquitination PhosphoSitePlus
K352 Ubiquitination PhosphoSitePlus
K411 Ubiquitination PhosphoSitePlus
K436 Ubiquitination PhosphoSitePlus
S466 Phosphorylation PhosphoSitePlus
T468 Phosphorylation HPRD   PhosphoSitePlus 18767875
K475 Ubiquitination PhosphoSitePlus
S480 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K161 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S255 F255 Biomuta DOID:4159 / skin cancer [ cosmic ]
K475 N475 Biomuta DOID:10534 / stomach cancer [ cosmic ]