iPTMnet Report for Q8TCD5 (NT5C)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8TCD5 / NT5C_HUMAN
Protein Name 5'(3')-deoxyribonucleotidase, cytosolic type
Gene Name Name: NT5C
Synonyms:DNT1,UMPH2;
Organism Homo sapiens (Human)

PRO ID PR:Q8TCD5
DAG View
PRO Name 5'(3')-deoxyribonucleotidase, cytosolic type (human)
Definition A 5'(3')-deoxyribonucleotidase, cytosolic type that is encoded in the genome of human.
Short Label hNT5C
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8TCD5 (NT5C) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S63 Phosphorylation PhosphoSitePlus
Y65 Phosphorylation PhosphoSitePlus
C108 Methylation IEDB 31844290
K112 Acetylation PhosphoSitePlus
K112 Ubiquitination PhosphoSitePlus
K134 Ubiquitination PhosphoSitePlus
K146 Acetylation PhosphoSitePlus
K146 Ubiquitination PhosphoSitePlus
S182 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19690332
S184 Phosphorylation PhosphoSitePlus
K194 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S182 Phosphorylation HPRD 18669648, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S63 R63 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
C108 S108 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]