iPTMnet Report for Q8TCB7 (METTL6)
Protein Information
| UniProt AC / UniProt ID | Q8TCB7 / METL6_HUMAN |
| Protein Name | tRNA N(3)-methylcytidine methyltransferase METTL6 |
| Gene Name | Name: METTL6 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8TCB7 |
| PRO Name | tRNA N(3)-methylcytidine methyltransferase METTL6 (human) |
| Definition | A tRNA N(3)-methylcytidine methyltransferase METTL6 that is encoded in the genome of human. |
| Short Label | hMETTL6 |
| Category | organism-gene |
Q8TCB7 (METTL6) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K33 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K120 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S204 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S274 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S284 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S204 | R204 | Biomuta | DOID:2531 / hematologic cancer [ cosmic, icgc ] |
DAG View