iPTMnet Report for Q8TC92 (ENOX1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8TC92 / ENOX1_HUMAN
Protein Name Ecto-NOX disulfide-thiol exchanger 1
Gene Name Name: ENOX1
ORFNames:PIG38;
Organism Homo sapiens (Human)

PRO ID PR:Q8TC92
DAG View
PRO Name ecto-NOX disulfide-thiol exchanger 1 (human)
Definition An ecto-NOX disulfide-thiol exchanger 1 that is encoded in the genome of human.
Short Label hENOX1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8TC92 (ENOX1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S254 Phosphorylation PhosphoSitePlus
K272 Ubiquitination PhosphoSitePlus
S299 Phosphorylation PhosphoSitePlus
S312 O-Glycosylation GlyGen 36240223
S403 Phosphorylation PhosphoSitePlus
S410 Phosphorylation PhosphoSitePlus
T412 Phosphorylation PhosphoSitePlus
S435 Phosphorylation PhosphoSitePlus
Y443 Phosphorylation PhosphoSitePlus
T465 Phosphorylation PhosphoSitePlus
T476 Phosphorylation PhosphoSitePlus
K502 Ubiquitination PhosphoSitePlus
T622 Phosphorylation PhosphoSitePlus
T627 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S254 P254 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S299 Y299 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S299 F299 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y443 C443 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
T465 N465 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T622 M622 Biomuta [ cosmic ] DOID:4159 / skin cancer [ cosmic ]
T627 M627 Biomuta DOID:1793 / pancreatic cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ]