Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8TC59 / PIWL2_HUMAN
Protein Name Piwi-like protein 2
Gene Name Name: PIWIL2
Synonyms:HILI;
Organism Homo sapiens (Human)

PRO ID PR:Q8TC59
DAG View
PRO Name piwi-like protein 2 (human)
Definition A piwi-like protein 2 that is encoded in the genome of human.
Short Label hPIWIL2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8TC59 (PIWIL2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R76 Methylation PhosphoSitePlus
R146 Methylation PhosphoSitePlus
R158 Methylation PhosphoSitePlus
T222 Phosphorylation PhosphoSitePlus
S299 Phosphorylation PhosphoSitePlus
S303 Phosphorylation PhosphoSitePlus
T309 Phosphorylation PhosphoSitePlus
S316 Phosphorylation PhosphoSitePlus
S637 Phosphorylation PhosphoSitePlus
T651 Phosphorylation PhosphoSitePlus
Y652 Phosphorylation PhosphoSitePlus
Y772 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T309 A309 Biomuta DOID:1793 / pancreatic cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
Y772 C772 Biomuta DOID:10534 / stomach cancer [ tcga ]