iPTMnet Report for Q8TC12 (RDH11)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8TC12 / RDH11_HUMAN
Protein Name Retinol dehydrogenase 11
Gene Name Name: RDH11
Synonyms:ARSDR1,PSDR1,SDR7C1;ORFNames:CGI-82;
Organism Homo sapiens (Human)

PRO ID PR:Q8TC12
DAG View
PRO Name retinol dehydrogenase 11 (human)
Definition A retinol dehydrogenase 11 that is encoded in the genome of human.
Short Label hRDH11
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8TC12 (RDH11) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y18 Phosphorylation PhosphoSitePlus
K26 Ubiquitination PhosphoSitePlus
T47 Phosphorylation PhosphoSitePlus
T51 Phosphorylation PhosphoSitePlus
K55 Ubiquitination PhosphoSitePlus
K59 Ubiquitination PhosphoSitePlus
K77 Ubiquitination PhosphoSitePlus
K83 Ubiquitination PhosphoSitePlus
T89 Phosphorylation PhosphoSitePlus
K98 Acetylation PhosphoSitePlus
K98 Ubiquitination PhosphoSitePlus
K105 Ubiquitination PhosphoSitePlus
S106 Phosphorylation PhosphoSitePlus
K112 Acetylation PhosphoSitePlus   UniProt 19608861
K112 Ubiquitination PhosphoSitePlus
K165 Ubiquitination PhosphoSitePlus
N174 N-Glycosylation GlyGen 24190977
K194 Ubiquitination PhosphoSitePlus
Y196 Phosphorylation PhosphoSitePlus
C203 Methylation IEDB 31844290
S205 Phosphorylation PhosphoSitePlus
K206 Ubiquitination PhosphoSitePlus
K221 Ubiquitination PhosphoSitePlus
C287 Methylation IEDB 31844290
C310 Methylation IEDB 31844290
Site PTM Type PTM Enzyme Score Source PMID
S29 Phosphorylation HPRD 20068231
S30 Phosphorylation HPRD 20068231
T34 Phosphorylation HPRD 20068231
S35 Phosphorylation HPRD 20068231
T47 Phosphorylation HPRD 20068231
T51 Phosphorylation HPRD 20068231
Y196 Phosphorylation HPRD 19562805
S205 Phosphorylation HPRD 19562805


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K26 T26 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S29 Y29 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K55 R55 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
K77 Q77 Biomuta DOID:9256 / colorectal cancer [ icgc ]
K165 N165 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S205 R205 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S205 G205 Biomuta DOID:363 / uterine cancer [ icgc ]
S205 N205 Biomuta DOID:363 / uterine cancer [ icgc ]