Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8TC07 / TBC15_HUMAN
Protein Name TBC1 domain family member 15
Gene Name Name: TBC1D15
Organism Homo sapiens (Human)

PRO ID PR:Q8TC07
DAG View
PRO Name TBC1 domain family member 15 (human)
Definition A TBC1 domain family member 15 that is encoded in the genome of human.
Short Label hTBC1D15
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8TC07 (TBC1D15) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330
S8 Phosphorylation PhosphoSitePlus
Y13 Phosphorylation PhosphoSitePlus
Y19 Phosphorylation PhosphoSitePlus
S22 Phosphorylation PhosphoSitePlus
S23 Phosphorylation PhosphoSitePlus   UniProt 24275569
K26 Ubiquitination PhosphoSitePlus
Y65 Phosphorylation PhosphoSitePlus
K68 Ubiquitination PhosphoSitePlus
S70 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19690332
S71 Phosphorylation PhosphoSitePlus
S72 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K81 Ubiquitination PhosphoSitePlus
S88 Phosphorylation PhosphoSitePlus
S93 Phosphorylation PhosphoSitePlus
S105 Phosphorylation PhosphoSitePlus
K107 Ubiquitination PhosphoSitePlus
K109 Ubiquitination PhosphoSitePlus
K125 Ubiquitination PhosphoSitePlus
S127 Phosphorylation PhosphoSitePlus
S131 Phosphorylation PhosphoSitePlus
K171 Ubiquitination PhosphoSitePlus
K179 Ubiquitination PhosphoSitePlus
S186 Phosphorylation PhosphoSitePlus
K190 Ubiquitination PhosphoSitePlus
S205 Phosphorylation PhosphoSitePlus
Y215 Phosphorylation PhosphoSitePlus
K239 Ubiquitination PhosphoSitePlus
K240 Ubiquitination PhosphoSitePlus
Y243 Phosphorylation PhosphoSitePlus
T244 Phosphorylation PhosphoSitePlus
T246 Phosphorylation PhosphoSitePlus
T254 Phosphorylation PhosphoSitePlus
Y256 Phosphorylation PhosphoSitePlus
S260 Phosphorylation PhosphoSitePlus
S264 Phosphorylation PhosphoSitePlus
S274 Phosphorylation PhosphoSitePlus   UniProt 23186163
K288 Ubiquitination PhosphoSitePlus
K324 Ubiquitination PhosphoSitePlus
K339 Ubiquitination PhosphoSitePlus
K369 Ubiquitination PhosphoSitePlus
K379 Ubiquitination PhosphoSitePlus
Y383 Phosphorylation PhosphoSitePlus
K387 Ubiquitination PhosphoSitePlus
K391 Ubiquitination PhosphoSitePlus
S394 Phosphorylation PhosphoSitePlus
K399 Ubiquitination PhosphoSitePlus
K413 Ubiquitination PhosphoSitePlus
K580 Ubiquitination PhosphoSitePlus
Y582 Phosphorylation PhosphoSitePlus
K589 Ubiquitination PhosphoSitePlus
K597 Ubiquitination PhosphoSitePlus
K606 Ubiquitination PhosphoSitePlus
S611 Phosphorylation PhosphoSitePlus
K616 Ubiquitination PhosphoSitePlus
S633 Phosphorylation PhosphoSitePlus
T637 Phosphorylation PhosphoSitePlus
S640 Phosphorylation PhosphoSitePlus   UniProt 24275569
S660 Phosphorylation PhosphoSitePlus
S669 Phosphorylation PhosphoSitePlus
S675 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 16964243, ...18669648, 24275569, 20068231, 17081983
T677 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S682 Phosphorylation PhosphoSitePlus
C686 S-Nitrosylation dbSNO 26338901
T689 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
Site PTM Type PTM Enzyme Score Source PMID
K200 Ubiquitination PhosphoSitePlus
S201 Phosphorylation PhosphoSitePlus
S203 Phosphorylation PhosphoSitePlus
S205 Phosphorylation PhosphoSitePlus
Y215 Phosphorylation PhosphoSitePlus
K220 Ubiquitination PhosphoSitePlus
Y226 Phosphorylation PhosphoSitePlus
S257 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S71 I71 Biomuta DOID:3571 / liver cancer [ icgc ]
K171 E171 Biomuta DOID:11934 / head and neck cancer [ icgc, tcga ]
S260 N260 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
S274 * Biomuta DOID:5041 / esophageal cancer [ icgc ]
K413 E413 Biomuta DOID:263 / kidney cancer [ tcga ]
K589 N589 Biomuta DOID:3070 / malignant glioma [ tcga ]
K616 * Biomuta DOID:3070 / malignant glioma [ tcga ]
T637 K637 Biomuta DOID:3070 / malignant glioma [ tcga ]
S640 L640 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc, tcga ]
S669 C669 Biomuta DOID:5041 / esophageal cancer [ icgc ]
S682 P682 Biomuta DOID:363 / uterine cancer [ tcga ]
T689 I689 Biomuta DOID:1909 / melanoma [ icgc, tcga ]