iPTMnet Report for Q8TC05 (MDM1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8TC05 / MDM1_HUMAN
Protein Name Nuclear protein MDM1
Gene Name Name: MDM1
Organism Homo sapiens (Human)

PRO ID PR:Q8TC05
DAG View
PRO Name nuclear protein MDM1 (human)
Definition A nuclear protein MDM1 that is encoded in the genome of human.
Short Label hMDM1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8TC05 (MDM1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K6 Methylation PhosphoSitePlus
S29 Phosphorylation PhosphoSitePlus
K48 Ubiquitination PhosphoSitePlus
S51 Phosphorylation PhosphoSitePlus
S83 Phosphorylation PhosphoSitePlus   UniProt 24275569
S109 Phosphorylation PhosphoSitePlus
S132 Phosphorylation PhosphoSitePlus
Y234 Phosphorylation PhosphoSitePlus
S242 Phosphorylation PhosphoSitePlus   UniProt 23186163
S263 Phosphorylation PhosphoSitePlus   UniProt 23186163
T294 Phosphorylation PhosphoSitePlus
K297 Ubiquitination PhosphoSitePlus
S314 Phosphorylation PhosphoSitePlus
S356 Phosphorylation PhosphoSitePlus
T408 Phosphorylation PhosphoSitePlus
S503 Phosphorylation PhosphoSitePlus
S504 Phosphorylation PhosphoSitePlus
S506 Phosphorylation PhosphoSitePlus
T515 Phosphorylation PhosphoSitePlus
S543 Phosphorylation PhosphoSitePlus
T572 Phosphorylation PhosphoSitePlus
K573 Methylation PhosphoSitePlus
K574 Methylation PhosphoSitePlus
S584 Phosphorylation PhosphoSitePlus   UniProt 23186163
K590 Ubiquitination PhosphoSitePlus
S601 Phosphorylation PhosphoSitePlus
S631 Phosphorylation PhosphoSitePlus
S648 Phosphorylation PhosphoSitePlus   UniProt 23186163
S683 Phosphorylation PhosphoSitePlus
S686 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S263 Phosphorylation HPRD 19007248
S503 Phosphorylation HPRD 20166139
S504 Phosphorylation HPRD 20166139, 17924679
S506 Phosphorylation HPRD 17924679


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S132 * Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
T294 I294 Biomuta DOID:4159 / skin cancer [ cosmic ]
K297 I297 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K590 * Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S601 F601 Biomuta DOID:4159 / skin cancer [ cosmic ]
S631 C631 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S683 F683 Biomuta DOID:1319 / brain cancer [ icgc ]