iPTMnet Report for Q8TBZ6 (TRMT10A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8TBZ6 / TM10A_HUMAN
Protein Name tRNA methyltransferase 10 homolog A
Gene Name Name: TRMT10A
Synonyms:RG9MTD2;
Organism Homo sapiens (Human)

PRO ID PR:Q8TBZ6
DAG View
PRO Name tRNA methyltransferase 10 homolog A (human)
Definition A tRNA methyltransferase 10 homolog A that is encoded in the genome of human.
Short Label hTRMT10A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8TBZ6 (TRMT10A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S28 Phosphorylation PhosphoSitePlus
S84 Phosphorylation PhosphoSitePlus
T144 Phosphorylation PhosphoSitePlus
C285 S-Nitrosylation dbSNO 26338901
S294 Phosphorylation PhosphoSitePlus
S302 Phosphorylation PhosphoSitePlus
S304 Phosphorylation PhosphoSitePlus
S306 Phosphorylation PhosphoSitePlus
S307 Phosphorylation PhosphoSitePlus
Y311 Phosphorylation PhosphoSitePlus
S312 Phosphorylation PhosphoSitePlus
S318 Phosphorylation HPRD   PhosphoSitePlus 19651622
S336 Phosphorylation PhosphoSitePlus   UniProt 23186163


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S28 N28 Biomuta DOID:4159 / skin cancer [ cosmic ]
S302 L302 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:4159 / skin cancer [ cosmic, icgc ]
S307 T307 Biomuta DOID:1324 / lung cancer [ cosmic ]
S318 L318 Biomuta DOID:4159 / skin cancer [ cosmic ]
S336 F336 Biomuta DOID:9256 / colorectal cancer [ cosmic ]