iPTMnet Report for Q8TBK2 (SETD6)
Protein Information
| UniProt AC / UniProt ID | Q8TBK2 / SETD6_HUMAN |
| Protein Name | N-lysine methyltransferase SETD6 |
| Gene Name | Name: SETD6 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8TBK2 |
| PRO Name | N-lysine methyltransferase SETD6 (human) |
| Definition | An N-lysine methyltransferase SETD6 that is encoded in the genome of human. |
| Short Label | hSETD6 |
| Category | organism-gene |
DAG ViewQ8TBK2 (SETD6) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K39 | Methylation | score2 | UniProt | 30189201 | ||
| K39 | Methylation | Q8TBK2 (SETD6) | score2 | UniProt | 30189201 | |
| K39 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S118 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S120 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S138 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K179 | Methylation | score2 | UniProt | 30189201 | ||
| K179 | Methylation | Q8TBK2 (SETD6) | score2 | UniProt | 30189201 | |
| K327 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K372 | Methylation | score2 | UniProt | 30189201 | ||
| K372 | Methylation | Q8TBK2 (SETD6) | score2 | UniProt | 30189201 | |
| K385 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K394 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K441 | Ubiquitination | score1 | PhosphoSitePlus |
Q8TBK2 (SETD6) as PTM Enzyme
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K179 | N179 | Biomuta | DOID:9253 / gastrointestinal stromal tumor [ cosmic ] |
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