iPTMnet Report for Q8TBC3 (SHKBP1)
Protein Information
UniProt AC / UniProt ID | Q8TBC3 / SHKB1_HUMAN |
Protein Name | SH3KBP1-binding protein 1 |
Gene Name | Name: SHKBP1 Synonyms:SB1;ORFNames:PP203; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8TBC3 |
PRO Name | SH3KBP1-binding protein 1 (human) |
Definition | An SH3KBP1-binding protein 1 that is encoded in the genome of human. |
Short Label | hSHKBP1 |
Category | organism-gene |
Q8TBC3 (SHKBP1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
A2 | Acetylation | score1 | UniProt | 22814378 | ||
K28 | Ubiquitination | score1 | PhosphoSitePlus | |||
T70 | Phosphorylation | score1 | IEDB | 35494241 | ||
K82 | Ubiquitination | score1 | PhosphoSitePlus | |||
K138 | Ubiquitination | score1 | PhosphoSitePlus | |||
S144 | Phosphorylation | score1 | PhosphoSitePlus | |||
S161 | Phosphorylation | score1 | PhosphoSitePlus | |||
T163 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
K181 | Ubiquitination | score1 | PhosphoSitePlus | |||
S185 | Phosphorylation | score1 | PhosphoSitePlus | |||
S187 | Phosphorylation | score1 | PhosphoSitePlus | |||
C216 | Methylation | score1 | IEDB | 31844290 | ||
K359 | Ubiquitination | score1 | PhosphoSitePlus | |||
K435 | Ubiquitination | score1 | PhosphoSitePlus | |||
T472 | Phosphorylation | score1 | PhosphoSitePlus | |||
K512 | Ubiquitination | score1 | PhosphoSitePlus | |||
C605 | Methylation | score1 | IEDB | 31844290 | ||
S624 | Phosphorylation | score1 | PhosphoSitePlus | |||
S637 | Phosphorylation | score1 | PhosphoSitePlus | |||
S640 | Phosphorylation | score1 | PhosphoSitePlus | |||
S647 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S649 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18669648, 23186163 | ||
R658 | Methylation | score1 | PhosphoSitePlus | |||
S662 | Phosphorylation | score1 | PhosphoSitePlus | |||
R679 | Methylation | score1 | PhosphoSitePlus | |||
T682 | Phosphorylation | score1 | PhosphoSitePlus | |||
T693 | Phosphorylation | score1 | PhosphoSitePlus | |||
T696 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K28 | N28 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
K82 | Q82 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K138 | N138 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
T163 | M163 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
S185 | * | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic ] | |
S187 | * | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
K359 | * | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
T472 | P472 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
S624 | L624 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
S640 | F640 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S647 | I647 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
R658 | H658 | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic ] | |
R679 | L679 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |