iPTMnet Report for Q8TBC3 (SHKBP1)
Protein Information
| UniProt AC / UniProt ID | Q8TBC3 / SHKB1_HUMAN |
| Protein Name | SH3KBP1-binding protein 1 |
| Gene Name | Name: SHKBP1 Synonyms:SB1;ORFNames:PP203; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8TBC3 |
| PRO Name | SH3KBP1-binding protein 1 (human) |
| Definition | An SH3KBP1-binding protein 1 that is encoded in the genome of human. |
| Short Label | hSHKBP1 |
| Category | organism-gene |
Q8TBC3 (SHKBP1) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| A2 | Acetylation | score1 | UniProt | 22814378 | ||
| K28 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T70 | Phosphorylation | score1 | IEDB | 35494241 | ||
| K82 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K138 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S144 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S161 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T163 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| K181 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S185 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S187 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C216 | Methylation | score1 | IEDB | 31844290 | ||
| K359 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K435 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T472 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K512 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C605 | Methylation | score1 | IEDB | 31844290 | ||
| S624 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S637 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S640 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S647 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| S649 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18669648, 23186163 | ||
| R658 | Methylation | score1 | PhosphoSitePlus | |||
| S662 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R679 | Methylation | score1 | PhosphoSitePlus | |||
| T682 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T693 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T696 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K28 | N28 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
| K82 | Q82 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| K138 | N138 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| T163 | M163 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| S185 | * | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic ] | |
| S187 | * | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
| K359 | * | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
| T472 | P472 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
| S624 | L624 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
| S640 | F640 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S647 | I647 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| R658 | H658 | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic ] | |
| R679 | L679 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |
DAG View