iPTMnet Report for Q8TBB1 (LNX1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8TBB1 / LNX1_HUMAN
Protein Name E3 ubiquitin-protein ligase LNX
Gene Name Name: LNX1
Synonyms:LNX,PDZRN2;ORFNames:UNQ574/PRO1136;
Organism Homo sapiens (Human)

PRO ID PR:Q8TBB1
DAG View
PRO Name E3 ubiquitin-protein ligase LNX (human)
Definition An E3 ubiquitin-protein ligase LNX that is encoded in the genome of human.
Short Label hLNX1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8TBB1 (LNX1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
C118 Methylation IEDB 31844290
S236 Phosphorylation PhosphoSitePlus
S238 Phosphorylation PhosphoSitePlus
T354 Phosphorylation PhosphoSitePlus
S379 Phosphorylation PhosphoSitePlus
S441 Phosphorylation PhosphoSitePlus   UniProt 23186163
S468 Phosphorylation PhosphoSitePlus
T493 Phosphorylation PhosphoSitePlus
T502 Phosphorylation PhosphoSitePlus
T554 Phosphorylation PhosphoSitePlus
T567 Phosphorylation PhosphoSitePlus
S570 Phosphorylation PhosphoSitePlus
S572 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y88 Phosphorylation HPRD 9535908


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y88 N88 Biomuta DOID:1324 / lung cancer [ cosmic ]
S379 G379 Biomuta [ cosmic ]
S468 I468 Biomuta DOID:1324 / lung cancer [ cosmic ]
T493 I493 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T567 I567 Biomuta DOID:10534 / stomach cancer [ cosmic ]