iPTMnet Report for Q8TB92 (HMGCLL1)
Protein Information
| UniProt AC / UniProt ID | Q8TB92 / HMGC2_HUMAN |
| Protein Name | 3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic |
| Gene Name | Name: HMGCLL1 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8TB92 |
| PRO Name | 3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic (human) |
| Definition | A 3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic that is encoded in the genome of human. |
| Short Label | hHMGCLL1 |
| Category | organism-gene |
DAG ViewQ8TB92 (HMGCLL1) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| G2 | Myristoylation | score2 | UniProt | 22865860 | ||
| S13 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K260 | Acetylation | score1 | PhosphoSitePlus |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S27 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T38 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| G2 | E2 | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic ] | |
| S27 | * | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| K260 | Q260 | Biomuta | DOID:363 / uterine cancer [ icgc ] |
